Enrichment P- value Probe set Entrez ID Title Symbol 1 - up 393 LN only _at necdin-like 2 Ndnl2

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1 393LN/344SQ/393P gene set Gene set overlap Total in set Enrichment P- value Probe set Entrez ID Title Symbol 1 - up 393 LN only _at necdin-like 2 Ndnl2 1 - up 393 LN only _at up 393 LN only _at up 393 LN only _at regulating synaptic membrane exocytosis 2 cirrhosis, autosomal recessive 1A (human) RAN binding protein 2 Rims2 Cirh1a Ranbp2 1 - up 393 LN only _s_at regulating synaptic membrane exocytosis 2 Rims2 1 - up 393 LN only _at down 393 LN only _at up 344 SQ only _at sorbin and SH3 domain containing 2 Sorbs2 imprinted and ancient Impact 3 - up 344 SQ only _at up 344 SQ only _at up 344 SQ only _at up 344 SQ only _at up 344 SQ only _at --- member 2 ankyrin repeat domain 15 Serpinb2 Ankrd15 ring finger (C3HC4 type) and KH domain containing 1 Rkhd1 suppressor of cytokine signaling 2 Socs2 2 days neonate sympathetic ganglion cdna, RIKEN full-length enriched library, clone: a1 9 product:unclassifi able, full insert sequence up 344 SQ only _a_at potassium voltagegated channel, shaker-related subfamily, beta member 1 Kcnab1 3 - up 344 SQ only _at suppressor of cytokine signaling 2 Socs2 3 - up 344 SQ only _at interleukin 11 Il up 344 SQ only _at

2 3 - up 344 SQ only _at up 344 SQ only _at up 344 SQ only _at calcium channel, voltagedependent, beta 2 subunit Cacnb2 zinc finger protein 9 Zfp9 zinc finger protein 462 Zfp down 344 SQ only E _a_at tumor-associated calcium signal transducer 1 Tacstd1 4 - down 344 SQ only E _at sphingomyelin phosphodiesteras e, acid-like 3B Smpdl3b 4 - down 344 SQ only E _at frizzled homolog 6 (Drosophila) Fzd6 4 - down 344 SQ only E _at F-box protein 32 Fbxo down 344 SQ only E _at RAB25, member RAS oncogene family Rab down 344 SQ only E _at suppression of tumorigenicity 14 (colon carcinoma) St down 344 SQ only E _at claudin 4 Cldn4 4 - down 344 SQ only E _at interferon regulatory factor 6 Irf6 4 - down 344 SQ only E _s_at G protein-coupled receptor 124 Gpr down 344 SQ only E _at chemokine (C-X-C motif) ligand 7 Cxcl7 4 - down 344 SQ only E _at plakophilin 3 Pkp3 4 - down 344 SQ only E _at down 344 SQ only E _at down 344 SQ only E _at down 344 SQ only E _a_at sarcoglycan, beta (dystrophinassociated glycoprotein) sarcoglycan, beta (dystrophinassociated glycoprotein) kallikrein related 8 immunoglobulin superfamily, member 9 Sgcb Sgcb Klk8 Igsf9 4 - down 344 SQ only E _at sema domain, immunoglobulin domain (Ig), domain (TM) and short cytoplasmic domain, (semaphorin) 4D Sema4d

3 4 - down 344 SQ only E _at wingless-related MMTV integration site 7B Wnt7b 4 - down 344 SQ only E _a_at down 344 SQ only E _a_at enabled homolog (Drosophila) member 5 Enah Serpinb5 4 - down 344 SQ only E _at down 344 SQ only E _at potassium channel, subfamily K, member 5 Kcnk5 CDC42 effector protein (Rho GTPase binding) 3 Cdc42ep3 4 - down 344 SQ only E _s_at toll-like receptor 3 Tlr3 NIPA-like domain 4 - down 344 SQ only E _at containing 2 Npal2 4 - down 344 SQ only E _at enabled homolog (Drosophila) Enah enabled homolog 4 - down 344 SQ only E _at (Drosophila) Enah 4 - down 344 SQ only E _at syntaxin 3 Stx3 4 - down 344 SQ only E _at C130090K23 gene 4 - down 344 SQ only E _a_at claudin 3 Cldn3 4 - down 344 SQ only E _at CUB domain containing protein 1 Cdcp1 C130090K23R 4 - down 344 SQ only E _at channel-like gene family 4 Tmc4 4 - down 344 SQ only E _at angiomotin-like 1 Amotl1 4 - down 344 SQ only E _at O05 gene /// similar to downregulated in ovarian cancer 1 isoform 2 /// similar to downregulated in ovarian cancer /// 6isoform O05R 4 - down 344 SQ only E _at L07 gene L07R

4 4 - down 344 SQ only E _at ribosomal protein S6 kinase polypeptide 6 Rps6ka6 4 - down 344 SQ only E _at copine VIII Cpne8 4 - down 344 SQ only E _a_at copine VIII Cpne8 4 - down 344 SQ only E _a_at EPS8-like 1 Eps8l1 4 - down 344 SQ only E _s_at and coiled coil domains 3 Tmcc3 4 - down 344 SQ only E _at syntaxin 3 Stx3 4 - down 344 SQ only E _a_at claudin 3 Cldn3 4 - down 344 SQ only E _at small nucleolar RNA, H/ACA box 65 Snora down 344 SQ only E _at down 344 SQ only E _a_at days neonate cerebellum cdna, RIKEN full-length enriched library, clone: f18 product:unclassifi able, full insert sequence --- A630095E13 gene A630095E13R 4 - down 344 SQ only E _at protocadherin 19 Pcdh down 344 SQ only E _x_at L07 gene /// A430108E01 gene /// similar to p /// 3protein isoform a L07R hook homolog down 344 SQ only E _at (Drosophila) Hook1 4 - down 344 SQ only E _at ankyrin repeat domain 56 Ankrd down 344 SQ only E _x_at member 5 Serpinb5 4 - down 344 SQ only E _at lymphocyte antigen 6 complex, locus E Ly6e

5 4 - down 344 SQ only E _at down 344 SQ only E _x_at Mammary gland RCB-0527 Jyg- MC(B) cdna, RIKEN full-length enriched library, clone:g930041p0 3 product:unclassifi able, full insert sequence --- member 5 Serpinb5 4 - down 344 SQ only E _at --- Transcribed locus down 344 SQ only E _at down 344 SQ only E _at expressed sequence AW AW down 344 SQ only E _at claudin 7 Cldn7 4 - down 344 SQ only E _at down 344 SQ only E _at potassium channel, subfamily K, member 1 Kcnk1 caspase recruitment domain family, member 10 Card down 344 SQ only E _at --- Transcribed locus down 344 SQ only E _at a disintegrin-like and metallo (reprolysin type) with thrombospondin type 1 motif, 1 Adamts1 4 - down 344 SQ only E _x_at claudin 3 Cldn3 4 - down 344 SQ only E _at MARVEL (membraneassociating) domain containing 3 Marveld3 4 - down 344 SQ only E _at L13 gene L13R 4 - down 344 SQ only E _s_at lymphocyte antigen 6 complex, locus E Ly6e 4 - down 344 SQ only E _at RNA binding motif protein 35A Rbm35a 4 - down 344 SQ only E _at SERTA domain containing 4 Sertad4 4 - down 344 SQ only E _at

6 4 - down 344 SQ only E _at p21 (CDKN1A)- activated kinase 6 Pak6 4 - down 344 SQ only E _at angiomotin-like 1 Amotl1 4 - down 344 SQ only E _x_at down 344 SQ only E _at D030056L22 gene D030056L22R tetratricopeptide repeat domain 9 Ttc9 4 - down 344 SQ only E _a_at potassium channel, subfamily K, member 1 Kcnk1 4 - down 344 SQ only E _at O15 gene O15R 4 - down 344 SQ only E _at protease, serine 11e Tmprss11e 4 - down 344 SQ only E _x_at claudin 3 Cldn3 5 - up both 393LN, 344 SQ _at up both 393LN, 344 SQ _at up both 393LN, 344 SQ _at up both 393LN, 344 SQ _at zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2 expressed sequence AI hypothetical LOC insulinomaassociated down both 393LN, 344 SQ _at nuclear factor, interleukin 3, regulated Nfil3 6 - down both 393LN, 344 SQ _a_at SKI-like Skil 6 - down both 393LN, 344 SQ _at down both 393LN, 344 SQ _at InaD-like (Drosophila) Inadl 6 - down both 393LN, 344 SQ _at up 393LN, down 344SQ _at Expressed sequence AI protein kinase C, mu Zrsr2 AI LOC Insm1 AI Prkcm 7 - up 393LN, down 344SQ _at D030056L22 gene D030056L22R 7 - up 393LN, down 344SQ _at up 393LN, down 344SQ _s_at up 393LN, down 344SQ _at cell division cycle 34 homolog (S. cerevisiae) Cdc34 Protein kinase C, mu Prkcm zinc finger protein 330 Zfp330

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