SLE5000 Neonatal Ventilator with High Frequency Oscillation

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1 SLE5000 Neonatal Ventilator with High Frequency Oscillation The SLE5000 is superb: the best High Frequency Ventilator I ve used When the smallest thing matters

2 SLE The Total Solution for Infant Ventilation The smallest thing does matter... There are still some neonates who cannot be adequately ventilated with even the most sophisticated conventional ventilation. Indeed, using conventional ventilation with higher rates and airway pressures has often led to an increased incidence of barotrauma and lung tissue damage. High Frequency Oscillation (HFO) has been shown to overcome this problem whilst still allowing excellent gaseous exchange. A proven technique Developed in cooperation with nurses and doctors, the SLE5000 uses a unique valveless system that gives both a manageable range of HFO parameters plus the ability to have active exhalation Of course, the SLE5000 still has all of the conventional ventilation modes meaning that it can be used on virtually any baby in the NICU User Interface SLE has always worked hard to make our ventilators easier to use. Essential functions are never more than a couple of button pushes away. Our own research has shown that users find it much easier to use a ventilator if there are fewer submenus. By reducing the number of menus and sub-menus the SLE5000 is even easier to use when time is critical. The SLE5000 has a high resolution colour touch-screen that is your interface to all the ventilator controls and functions, but in addition allows you to access many new features including trends and dynamic loops. The SLE5000 also features parameter presetting, meaning that you can choose a ventilation mode and set up all parameter values before accepting these and confirming the mode change. Fully Featured Modes include: CPAP, CMV+ TTV plus, PTV, PSV, SIMV+ TTV plus + PSV, HFO, HFO+CMV. Plus, the SLE5000 gives you: The ability to preset parameters in all modes of operation Powerful HFO with active expiration to cover a wide range of patients Full colour, total touch-screen operation Integral flow monitoring measuring lung mechanics and displaying of loops and waveforms Trending of measured parameters Standard patient circuit for all modes including HFO Unique, patented valveless technology Integral battery with up to 60 minutes operating capability Software based, allowing for upgrading to versions with new or improved functions Advanced Software If you already use an SLE5000 or SLE4000 ventilator then you will know just how versatile the range of installed modes can be, particularly on the SLE5000 where HFO allows you to include a considerably larger patient demographic than with conventional ventilation. Being software based, SLE s engineers are always trying to improve the algorithms they use in respect of new developments in medicine and userfeedback. Version 4.3 software does just that. Introduced with new ventilators in 2009, the software can still be installed in older ventilators. Version 4.3 Software Standard on all new SLE5000 and SLE4000 ventilators TTV plus Leak compensation MAP in HFO Battery indicator Mute all alarms CPAP mode alarms Can be installed on existing SLE5000 (and SLE4000) ventilators

3 Comprehensive Ventilation Features Targeted Tidal Volume plus (TTV plus ) The SLE5000 is our first production ventilator to feature TTV plus - an entirely new way of managing the patient s tidal volume. Lung protective ventilation strategies in neonates are now accepted as a marker for improved ventilation outcome. One such strategy is the use of a targeted tidal volume in pressure ventilation. The aim of TTV plus is to deliver a stable tidal volume at the lowest possible pressure. All this has to occur in the presence of a changing lung environment, that also has a potential for a variable leak around the ET tube. TTV plus approaches this challenge by assuring a stable expired volume, with a leak adjustment capability within safe limits. TTV plus can be used in all conventional ventilation modes and provides a stable tidal volume control according to your requirements. Pressure Support Ventilation (PSV) PSV was developed on the SLE5000 as a method to decrease the work of breathing in-between ventilator mandated breaths by providing an elevated pressure triggered by spontaneous breathing that supports ventilation during inspiration. Thus, SIMV might be combined with PSV so that additional breaths beyond the SIMV programmed breaths are supported. Whilst the SIMV mandated breaths have a preset volume or peak pressure, the PSV breaths are designed to cut short when the inspiratory flow reaches a percentage of the peak inspiratory flow (e.g. 0-50%). It includes automatic leak compensation thereby ensuring the flow termination of inspiration even in the presence of a leak. All of this means that breathing on the SLE5000 ventilator is even easier for the smallest of babies, allowing them more energy to grow. Without flow termination With flow termination High Frequency Oscillation (HFO) In the SLE5000, HFO is powerful enough to cater for a wide range of patients from 300 g to 20 kg, dependant on lung mechanics. The SLE5000 provides sinusoidal ventilation with active expiration. The main benefits of HFO include: Improves ventilation at lower pressures Higher levels of PEEP can be used without having to use high peak airway pressures to maintain appropriate levels of CO 2 Produces more uniform lung recruitment Reduces airleaks Improved oxygenation in infants with severe RDS

4 Features and Functions User Interface Colour-coded user touch screen. Easy-to-use, logical sequence allowing quick, smooth adjustments. The SLE5000 s 12 inch screen means that all the data you need can be easily seen. Mode Panel The mode panel is the user s interface to all mode related functions. Audible and Visual Alarms The alarm panel provides an immediate audible and pictorial view of the alarm condition, thus allowing easy monitoring, plus an alarm history of the last 100 conditions. Pre-Setting Facility Parameters can be preselected for the next mode whilst continuing to ventilate the patient in the current mode of ventilation. Patient Circuit Connections Front panel mounted patient circuit connections with (autoclavable) exhalation block. Principles of operation of the SLE5000 valveless system A constant flow of fresh gas is supplied to the patient circuit at 8 l/min. The expiratory manifold has three jets (➊, ➋ and ➌). The front jet (➊) is used to generate an opposing flow to the fresh gas in the exhalation manifold and thereby creates CPAP/PEEP. The rear jet (➋) is used to generate the Peak Inspired Pressure (PIP) in the same way. A third (reverse) jet (➌) is used during High Frequency Oscillation (to produce an active negative pressure) in addition to helping eliminate excess circuit pressure. To avoid gas dilution these jets are supplied with the same oxygen concentration as the fresh gas supply. Sophisticated software controls the rate and duration of the flow of driving gas into the exhalation manifold in opposition to the fresh gas flow. The opposing flow acts as a pneumatic piston and creates a pressure wave at the ET manifold. Since the opposing flow pressure is set by pressure regulators it automatically compensates for patient and circuit compliance changes.

5 Screen Pause Freezes waveforms for review. Graphic Select Allows display of real-time or trends of flow, pressure and volume. Loops depicting flow/volume, flow/pressure and volume/ pressure may also be shown. Night Mode and Screen Lock A low-level light mode for night time environments with automatic screen locking. Auto activation on an alarm condition. Real-time Data Display Real-time lung mechanics measurements and ventilatory data. This allows for continuous feedback for making crucial clinical decisions. Compact Unit The SLE5000 ventilator is housed in a one piece compact box, making it easier to clean and use. The integrated touch screen is angled for perfect visibility and easy to read from a distance. How does it work...? The illustration shows the exhalation block removed from its mountings in the ventilator. When replaced, the jets (➊ and ➋) can create a positive pressure on flow from the patient circuits s expiratory limb. ➌ ➋ ➊ Jet ➌ is used to create a negative pressure and gives true active expiration. Since there are no valves or other blockages in the system, there is minimal resistance to the patient. Fewer moving parts means there is less to clean and less risk in terms of wrong assembly or infection. To exhaust port Exhalation block From expiratory limb

6 SLE5000 Patient Circuits BC5188/100/15 Single use breathing circuit for use with SLE4000 and SLE5000 infant ventilators. Temperature port 100 mm from ET manifold (single use). Circuit comes complete with filter connection kit and adaptors. Sold in box quantity of 15 BC5188/400/15 Single use breathing circuit for use with SLE4000 and SLE5000 infant ventilators. Temperature port 400 mm from ET manifold (single use). Circuit comes complete with filter connection kit and adaptors. Sold in box quantity of 15 BC5288/DHW/15 Dual heated wire breathing circuit for use with SLE4000 and SLE5000 infant ventilators. Temperature port 400 mm from ET manifold (single use). Circuit comes complete with filter connection kit and adaptors. Sold in box quantity of 15 BC5488/DHW/15 Dual heated wire smooth bore breathing circuit for use with SLE4000 and SLE5000 infant ventilators. Temperature port 170 mm from ET manifold (single use). Circuit comes complete with filter connection kit and adaptors. Sold in box quantity of 15 BC6216 Nitric Oxide delivery kit, set of connectors. BC2508 Nebuliser kit. BC4110/KIT Nitric Oxide adaptor kit for BC5188/100 and BC5188/400 breathing circuits (SLE4000 and SLE5000 infant ventilators). Sold in box quantity of 5 BC4110/ASY Nitric Oxide dual hose scavenging filter assembly for SLE4000 and SLE5000 infant ventilators. Sold in box quantity of 1

7 Technical Specification Ventilation Modes: Conventional CPAP / PTV / PSV Inspiratory Time: 0.1 to 3.0 sec CPAP Pressure: 0 to 20 mbar Inspiratory Pressure: 0 to 65 mbar Volume Targeting: 2 to 200 ml FiO 2 : 21% to 100% CMV / SIMV BPM: 1 to 150 I:E Ratio: (11.2:1 to 1:600) Inspiratory Time: 0.1 to 3.0 sec PEEP Pressure: 0 to 20 mbar Inspiratory Pressure: 0 to 65 mbar Volume Targeting: 2 to 200 ml FiO 2 : 21% to 100% Ventilation Modes: HFO Ventilation HFO Only Frequency 3-20 Hz I:E Ratio: 1:1 Delta Pressure range: 4 to 180 mbar Mean airway range: 0 to 35 mbar FiO 2 : 21% to 100% HFO+CMV BPM: 1 to 150 Inspiratory Time: 0.1 to 3.0 Frequency 3-20 Hz I:E : (11.2:1 to 1:600) Inspiratory Pressure: 0 to 65 mbar Delta Pressure range: 4 to 180 mbar Mean airway range: 0 to 35 mbar FiO 2 : 21% to 100% Monitoring Parameters Measurement of Flow and Volume Flow Sensor Type: 10 mm dual-hotwire anemometer (autoclavable or single use) Flow Rate: 0.2 to 32 l/min (Accuracy ±8%) Expiratory Tidal Volume: 0 to 999 ml Expiratory Minute Volume: 0 to 18 litres Deadspace: 1 ml Weight: 10 g Conventional Ventilation and combined modes only: Tube Leakage: 0 to 50% ( 5%, averaged over 5 breaths) Breath Rate (total): 0 to 150 BPM Dynamic Compliance: 0 to 100 ml/mbar ( 1 ml/mbar) C20/C: Resolution 0.1 Sampling Time: 2 ms Resistance: 0 to 1000 mbar.second/l Triggering: Inspiratory flow (0.2 to 10 l/min) The above values are measured under ATPD (ambient temperature and pressure, dry) conditions. Oxygen Concentration 21 to 100% (Resolution 1%) Pressure Real-time Pressure measurement: Sampling time: Peak Pressure: PEEP Pressure: Mean Pressure: Resolution 1 mbar 2 ms 0 to 175 mbar (resolution 1 mbar) 0 to 175 mbar (resolution 1 mbar) -175 to 175 mbar (resolution 1 mbar) In HFO combined mode, Delta P is measured during expiration only User Settable Alarms: High Pressure Autoset when patient pressure controls are adjusted or can be manually adjustable 10 to 110 mbar 0.5 mbar Cycle Fail Autoset when patient pressure controls are adjusted or may be manually adjusted Low Pressure Autoset when patient pressure controls are adjusted or can be manually adjustable -10 mbar (Conventional) -70 mbar (HFO modes) to 10 mbar below high pressure threshold Low Tidal Volume Low Minute Volume High Minute Volume 0 to 200 ml 0.2 ml 0 to 0.02 litres below High Minute Volume threshold 0.1 litre 0.02 to 18 litres 0.1 litre Apnoea time Settable only in CPAP or when Backup rate is less than 20 BPM 3 to 60 sec 1 second Power, Dimensions, Standards etc. Power Requirements Voltage : V Hz Power : 115 VA Battery back up: minutes (dependant on mode of operation) Battery charging: Full charge 24 hours, 80% charge after 8 hours Outputs RS-232C Air and O 2 input Pressures: Fresh Gas Flow: Maximum gas flow: bar 8 litres/min 60 litres/min Operating Environment Temp: ºC Humidity: 0-90% (non-condensing) Dimensions Size, ventilator only: 330mm W x 330mm H x 470mm D Height on short stand: 114 cm Height on tall stand: 131 cm Weight, ventilator only: 22.4 kg Constructed to conform to: Constructed to conform to: BS EN : A1:93, A11:93, A12:93, A2:95, A13:96, Corrigendum: 94 BS EN : 2006 Medical Devices Directive (93/42/EEC) EMC BS EN : 2001+A1 BS EN : 2006 BS EN : A1 European conformity mark: CE 0120 Environmental storage conditions When packed for transport or storage: Ambient Temperature: -40 C to +70 C Relative Humidity : 10% to 90% (non-condensing) Atmospheric Pressure: 500 hpa to 1060 hpa

8 SLE is a world leader in the design and manufacture of neonatal ventilators. Years of ventilation experience have given the company an understanding of the challenges facing nurses and clinicians when caring for the tiniest and most critical babies. From being the pioneers of neonatal Patient Triggered Ventilation (PTV) in the 1980 s, to the introduction of combined HFO (High Frequency Oscillation) in the 1990 s, SLE has maintained a position of strength in neonatal ventilation. The company s guiding principle is to support clinical and nursing staff in their everyday work. The knowledge and experience gained during years of development is evident in the SLE5000 ventilator: the result of SLE s ongoing commitments to innovation, competency and care. For something so powerful, the SLE5000 is incredibly easy to use... SLE Limited. Twin Bridges Business Park, 232 Selsdon Road, South Croydon Surrey CR2 6PL UK Telephone:+44 (0) Fax: +44 (0) Web: CSD /10

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