APEX TM III MASS SPECTROMETER SITE GUIDE AND PRE-INSTALLATION INSTRUCTIONS

Transcription

1 APEX TM III MASS SPECTROMETER SITE GUIDE AND PRE-INSTALLATION INSTRUCTIONS NOTE: Important Facilities and Installation Data Within Please Forward to Cognizant Engineering or Using Department All measurements in millimeters Page 1 of 27

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3 1.0.0 INTRODUCTION It is advantageous for the user to make certain preliminary preparations prior to the arrival of the Bruker field service engineer. These arrangements vary according to the support equipment purchased. However, the basic installation is identical for all units. The basic installation preparations include: a. The selection of the location for the APEX TM III Mass Spectrometer. b. The utility installation necessary for its operation. c. Floor loading determination. d. A method of handling the magnet during installation. e. The purchase of the required cryogens (nitrogen and helium) The following are recommendations for the preparation of your site for the installation of a superconducting magnet FTMS spectrometer system. If any of these recommendations cannot be achieved, please contact your local Bruker service office as soon as possible so that alternate plans can be made prior to the beginning of the installation SELECTION OF THE LOCATION FOR THE MASS SPECTROMETER SAFETY CONSIDERATIONS Superconducting magnets can cause potential safety hazards due to their extended magnetic stray field, their large attractive forces on ferromagnetic objects, and their large content of cryogenic liquids. It is the sole responsibility of our customers to ensure safety in their FTMS laboratory and to comply with local safety regulations. Inc. (BDI) is not responsible for any injuries or damages due to an improper room layout or due to improper operation routines MAGNETIC ATTRACTIVE FORCES Strong attraction of ferromagnetic objects may occur at close distance to the magnet, where the magnetic field is above 50 to 100 Gauss. The attractive force depends on the mass of the object and on the distance from the magnet. It increases rapidly when the distance is reduced (by the 7th power). Hence, it may change from barely noticeable to uncontrollable in a very short distance. It is therefore very important that a safety space is established and marked around the magnet, and that all pathways in the FTMS room stay clear of that area. Massive iron objects such as pressurized gas cylinders used for GCMS, QEA, etc. are extremely dangerous in the vicinity of a superconducting magnet. They should be mounted very close to the door and away from the magnet, or even better, outside the magnet room. In the minimum they should remain outside the 5 gauss line as indicated by the field plots given in the Appendix in this document. Inside the room with the magnet, a wall mounted gas distribution system is recommended. Page 3 of 27

4 2.1.2 MAGNETIC STRAY FIELD It is generally accepted that stray fields are harmless below 3 to 5 Gauss (ten times the earth's magnetic field). Stronger stray fields closer to the magnet may disturb some heart pacemakers, erase magnetic cards and storage devices, and adversely affect watches and micro mechanical devices. It is therefore recommended to mark the 5 Gauss line around the magnet, display warning signs and to limit access to areas with more than 10 to 20 Gauss field to FTMS staff only. A safe location for mechanical watches, wallets, and software disks at the entrance to the FTMS laboratory or in a separate room is recommended for storage of these items by the FTMS staff. Be aware that the magnetic stray field extends in all three dimensions and is not affected by walls, floors, or ceilings. For FTMS magnets the horizontal extension is larger than the vertical one. High fields may also affect the rooms above and below the magnet. Local shielding of sensitive devices such as computer displays is possible in stray fields below 10 Gauss. Global shielding of the entire magnet stray field is usually very costly. However, stray fields can be greatly reduced by using a shielded magnet. Bruker strongly recommends the use of shielded magnets, especially in multi-user installations and facilities where access to the magnet cannot be easily restricted. Stray field plots and warning signs will be included with each magnet. Full stray field plots are also included in this document and extra copies of field plots or warning signs are also available from our customer service representative. A summary of the 5 and 10 gauss field lines for each system follows in table 1 as well as a summary of the effects of magnetic stray fields contained in table 2. Table 1: Stray field lines Magnet z - Axis (Field z Axis (Field Axis) Axis) x, y - Axis x, y - Axis 5 Gauss 10 Gauss 5 Gauss 10 Gauss APEX TM II m 0.8 m ** ** Passively Shielded APEX TM II m 1.4 m 0.7m 0.8m Actively Shielded APEX TM II m 1.7 m 1.1m 0.9m Actively Shielded APEX TM II-94 Actively Shielded 2.2m 2m 1.5m 1.4m ** Does not extend beyond magnet dewar. Page 4 of 27

5 Table 2: Summary of Magnetic Field Effects (level where damage can occur) Effects on electron microscopes 1 Gauss Disturbance of color computer displays* 1-3 Gauss Disturbance of monochrome computer displays 3-5 Gauss Erasing of credit cards and bank cards 10 Gauss Effects on watches and micro mechanical devices 10 Gauss Lowest known field effect on pace makers 1-7 Gauss Erasing of magnetic tapes 20 Gauss Saturation of transformers and amplifiers 50 Gauss Erasing of floppy diskettes or magnetic tape 350 Gauss *Disturbances of computer displays can be effectively reduced by shielding the display, as long as the field is below 10 Gauss RECOMMENDATIONS ON SAFETY These recommendations are adequate for industries and research institutes with limited public access. The general public should not be allowed access to areas with fields above 5 Gauss. No inexperienced persons (such as visitors, cleaning staff, electricians, plumbers, painters, etc.) should have access to the magnet without supervision by the FTMS staff. Table 3: Recommended Area Restrictions Warning signs (safety limit for medical devices) Access limited to FTMS staff only (safety limit for heavy iron objects) Floor markings (safety limit for attraction of iron) Pressurized gas cylinders (wall mounted) 5 Gauss 10 Gauss 5 Gauss 10 Gauss CRYOGENIC LIQUIDS Superconducting magnets use liquid Nitrogen and Helium as cooling agents. These liquids expand their volume by a factor of 700 during evaporation and warm-up. The gases are nontoxic and completely harmless as long as adequate ventilation is provided to avoid suffocation. During normal operation only 100 to 150 cubic feet per day of nitrogen are evaporated, but during a quench 1500 to 3500 cubic feet of helium gas are produced within a short time. Windows and doors are sufficient for ventilation even after a quench, but the magnet should never be in an airtight room. Room layout, room clearance and magnet height should be such that an easy transfer of liquid nitrogen and helium is possible. This will reduce the risks of accidents considerably. Page 5 of 27

6 2.2.0 OPERATIONAL CONSIDERATIONS The ease or difficulty of day-to-day operation depends strongly on the room dimensions and layout. Easy access to the magnet for refilling the cryogenic liquids and adequately located gas and power outlets are important. Room dimensions should be sufficient to allow convenient pathways around the magnet. The addition of auxiliary inlets and equipment such as GC, LC, ethernet connections, etc. should be taken into account at this time also. The minimum room height is given by the space needed for refilling helium. However some extra space makes handling much easier. Special short helium transfer lines are available, but they do have higher helium transfer losses. Large magnets require rooms with oversized doors to enable installation. Magnet dewars are shipped with support fixtures (shipping bungs), which must be removed at the installation site. This requires a suitable hoist with sufficient room height, which is generally more than the minimum required for helium transfer. If this cannot be done in the lab, the magnet system may be moved after assembling, however this will be done at the customers risk. There is no danger of damage to the magnet or dewar, but the very tight tolerances of alignment may be disturbed by moving a dewar after assembly. If so, it only shows up during the cool down or after energization. This requires the warming up and realignment of the dewar with a corresponding waste of much time and helium. The vacuum cart and electronics consoles require sufficient clearance around them to provide for adequate cooling. This space also allows for installation and service of the system which includes convenient changing of the optional sources, changing pump oils and general system maintenance. Please refer to Chapter for system specific recommended room layouts FLOOR LOADING The FTMS magnet system is quite heavy. Depending on field strength, bore diameter and specially the shielding, the weight may be 1,500 to 13,200 kg. The floor of the room must be strong enough to support the weight of the instrument allowing for a certain amount of mild vibration. In general, for field strengths of < 7.0 Tesla, the dead weight floor loading for the magnet is approximately 0.40 kg/cm2 for an unshielded magnet and 1.4 kg/cm2 for a shielded magnet. Please refer to Chapter for the exact footprint of each instrument model ELECTRIC POWER An important consideration when selecting the area for the Mass Spectrometer is availability of adequate power. The magnet system needs electric power only during charging and discharging and for the operation of the optional helium recovery system. Regardless of what accessory equipment is purchased for a particular installation, sufficient power should be brought into the area to provide for future needs. There are recommendations for power distribution located in Chapter 5.1.1, along with the floor layout. A complete APEX TM III Mass Spectrometer requires up to 20 KVA (please refer to Chapter for a explanation of the power consumptions of the various instrument configurations.) Bruker recommends Page 6 of 27

7 that one 3 phase five wire 380 V AC phase to phase, 30 Amp, 50 or 60 Hertz circuit (220 Volt to neutral) be available before the instrument arrives. Power distribution within the mass spectrometer consists of three 220V, 30A circuits-split off from the three phase 220 volt to neutral circuit If the only available power is 208 V AC (common in the United States) then a boost transformer (optionally available) must be installed to raise the output to 380 V AC. If this option is to be used, the transformer should be installed prior to the delivery of the instrument. For additional information on using the boost transformer please contact your sales/service office. If the line voltage fluctuations exceed +10% or -5%, a voltage regulator must be installed. A quick disconnect, in addition to the emergency kill switch on the system, may be required by safety codes in many areas. The customer is responsible for appropriate connection of the instrument to the outlets. The instrument is delivered with a long enough power cable without connector WATER The ultra high vacuum pumps in the mass spectrometer are water-cooled and require a continuous stream of water. Turbo-pumped systems require 150 Liter/hour of filtered, soft water that is not to exceed 20C. Cryopump systems require 200 Liter/hour of filtered, soft water that is not to exceed 20C. If filtered soft "house" water is used, a drain for the water is necessary. A constant pressure regulator on the water line is recommended if the water pressure is likely to change a large amount over a 24-hour period. Many communities prohibit the use of "house" water for cooling and require a closed loop heat exchange system. Bruker, due to environmental considerations, encourages the use of closed loop water chiller systems. Turbo pump systems require water chillers with a 500 W cooling capacity and 40psi supply pressure while cryo pump systems require water chiller with a 3 KW (or better) cooling capacity. Please note that cooling capacity for heat exchangers may depend on the room temperature. These specifications should be examined closely and possibly forwarded to your heat exchanger vendor, for a recommendation based on the proper requirements VENTILATION AND AIR CONDITIONING For most efficient operation, the mass spectrometer must be in an air-conditioned room where both temperature and humidity are controlled. It is important to note, a complete operating mass spectrometer will produce between 15 and 20,000 BTU/hr exclusive of other sources of heat. Room temperature must not exceed 72deg. F and should be maintained within ±10deg F for best performance of the FTMS spectrometer. Relative humidity should remain in the 40 to 60% range. If the air in the lab gets too damp high voltage arcing can be a problem as well as excessive condensation on the cryostats and cooling water lines. If it is too dry there are problems with static electricity. Ventilation should be adequate to avoid depletion of oxygen. Constant air temperature and pressure is very important for high performance operation. Rapid ambient pressure and temperature fluctuations reduce the performance of the FTMS spectrometer. If an air conditioning unit is installed, it should be far away from the magnet. The air in the vicinity of the magnet dewar should not be disturbed by drafts from an inlet or an outlet of the ventilation Page 7 of 27

8 system. If the optional water chiller is used as the source of cooling water for the turbo or cryopumps, the heat load due to these units must be taken into account when calculating the air conditioning capacity GASES Dry, oil and dust free, clean regulated pressurized air at 60 to 100 psi with a dew point of -40deg. F or lower is required for operation of the pneumatic valves on the vacuum system. For refilling the magnet dewar with cryogenic liquids both pressurized nitrogen and helium gas are also required. The electrospray ion source on the APEX TM III requires a source of dry nitrogen psi and 2 scfm and dry oxygen (for negative ions) at psi and 2 scfm. If no fixed gas supplies are available for refilling or the electrospray source, transportable cylinders may be used. However, if ferro-magnetic cylinders are used in the presence of strong magnetic fields, they may present a possible source of serious accidents. Non-magnetic liquid nitrogen cylinders with a pressure build-up system are convenient sources of dry nitrogen gas. Gas requirements for the optional GC inlet depend on the actual experiment planned. MS/MS experiments require a small cylinder of argon or another suitable collision gas LIQUID NITROGEN AND HELIUM A constant and dependable source of the liquid cryogens is essential to maintaining the magnetic field. Therefore, it will be necessary to arrange for the delivery of liquid nitrogen and helium if the facility does not have it readily available. These arrangements may be made through a local supplier of liquefied gases. Typical requirements for installation are: approx. 300 Liters (for 3 Tesla) to 1400 Liters (for the 9.4Tesla) of liquid Helium approx. 500 Liters (for 3 Tesla) to 1500 Liters (for the 9.4Tesla) of liquid Nitrogen Typical requirements for routine fills are: approx. 100 L of liquid He for refills every approx. 90 days approx. 75 L of liquid N2 for refills once per week Please refer to the individual Magnet specifications for exact numbers RADIO FREQUENCY INTERFERENCE RF interference can cause spikes in the spectra at any m/z ratio whose resonance frequency is close to the frequency of the interference. The most common source of RF interference is TV and AM radio stations. They broadcast at frequencies in the range of interest for FTMS (10 MHz to 10 KHz). Other possible sources can be paging systems, ham radio transmitters, arc welders, and other RF spectrometers. Due to the relationship of transmission power and distance radiated and since a common mode rejection of 80- Page 8 of 27

9 100 db is attainable in the receiver chain, these interferents are rarely a major problem RF interferents are often introduced on a poor power grounding coming into the FTMS laboratory TELEPHONE AND ETHERNET It is highly recommended that a telephone and ethernet be installed at the console site. It should be accessible to the operator of the instrument while seated at the console. This would be used for troubleshooting assistance as well as applications support. In addition, APEX TM III spectrometers with the UNIX or Windows NT based acquisition computer use an ethernet connection for remote diagnostics and remote software upgrades or correction of corrupt data, an ethernet line within reach of the computer is required for this function. For facilities where outside ethernet or telephone connection to computers is not permitted for security reasons, an outgoing only telephone line and a voice connection are recommended for remote diagnosis RECOMMENDATIONS FOR ROOM LAYOUT For safety reasons, the magnet should be located away from doors and in a location that the stray field of 10 to 20 Gauss does not extend beyond the room. Refilling of cryogenic liquids is more comfortable if the magnet system is easily accessible for the transport dewars and if adequately located gas outlets are available. The rate of nitrogen boil-off from the system depends on the dewar surface temperature; hence the dewar should not be located close to a heat source or in direct sunlight. The Computer workstation and the electronics console should be placed at sufficient distance from the magnet and oriented so that the display monitor, disk and other magnetic storage devices are on the far end from the magnet. Normally the magnet is located on the right side of the console. If a left hand system is required, this should be specified at the time of order. An installation and access space to the rear of the console and the right side of the vacuum system is recommended with a minimum clearance of 2 feet to the walls. Recommended room layouts are provided at the end of this guide OTHER CONSIDERATIONS In addition to the above, the following should be considered. Dust and corrosive gases or vapors are to be avoided if possible. The same consideration should be given to the mass spectrometer as would be given to any precision electrical equipment containing relays, meters, insulators, etc. The instrument presents no problems in this connection which are not encountered in other electrical and electronic equipment. Most biological samples require refrigeration for long and short-term storage. It is recommended that a freezer be located near the instrument for storage of biological samples and calibration compounds. However, when placing the refrigerator in the same vicinity as the magnet system, remember to maintain a distance from the 5 gauss stray field so the compressor of the refrigerator is not strained. Sufficient space for sample preparation, short-term storage of LC solvents, and storage of optional ion sources and inlets, spare parts and tools is desirable for day-to-day operation. Page 9 of 27

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11 3.0.0 PERFORMANCE CONSIDERATIONS Almost any site is suitable for routine FTMS operations and good performance may be achieved even with moderate environmental conditions of the FTMS room and its close vicinity. In general, higher performance is possible with FTMS in a given set of environmental conditions than is possible with other high resolution MS systems. Even so, ultra-high performance operation requires a very stable and constant environment. Top performance will only be achieved if you select an adequate magnet location. It is therefore recommended for large FTMS laboratories to plan ahead and influence the building construction in the planning phase. It should be considered that the trend will always be towards larger magnetic fields with inherently higher demands on the conditions of the installation site in order to maintain and optimal operation STATIC IRON DISTRIBUTION Static iron distribution in the vicinity of the magnet will exert a force on the magnet and disturb the field homogeneity in the FTMS cell. The force may disturb the very tight tolerances of alignment, if so, it shows up during the energizing of the magnet. In that case the magnet must be moved away from the iron. An increase in the distance of 25% is usually sufficient. Extended areas of iron with near constant density distributions generate rather harmless field disturbances. Their effects can easily be removed with the superconducting X, Y, and Z shims that are standard on Bruker systems. Concentrated iron objects, however, can produce rather strong local field variations, which are difficult to correct for. Since these may be corrected by shimming during installation, it is recommended that the location of any large iron objects such as gas cylinders be decided before installation so that they may be present at the installation. This aspect becomes more important for high field and wide bore magnets with extended stray fields. If the magnet must be located in the vicinity of iron or steel support beams, a proper alignment is important. Horizontal iron concentrations at heights close to the magnetic center and iron objects terminating near the magnet should be avoided. They lead to very asymmetric field disturbances. Since these are, in most cases, heating or plumbing devices rather than structural support beams, they may need to be removed before installation. Section 3.3 gives some examples of minimum distances, which should be considered for magnet positioning INTERFERENCE FROM VARIABLE MAGNETIC FIELDS Variable field effects are very difficult to eliminate. Therefore they should be considered early in the planning stage. Variations can originate from moving iron objects such as metal chairs, doors, handcarts, elevators, and cars. They also can be caused by electromagnetic equipment, from power lines carrying DC currents or from floor vibrations or oscillations of the entire building. The most disturbing fluctuations are step-like field changes produced by large switching DC currents from subways, trolley cars, etc. or from field ramping mass spectrometers during fly-back of the field. If you have any of these near your site contact Bruker for a magnetic interference survey of the lab as early in the planning stage Page 11 of 27

12 as possible. In general, mass calibration of the FTMS spectrometer is not affected if the variation of a moving iron object occurs outside of the 5 gauss line for the magnet used in the system SUMMARY OF MAGNETIC FIELD DISTURBANCES: Table 4: Stray field or distance from the magnet at which effects may occur Force from large iron objects of over 2000 lbs. Force from iron objects over 400 Lbs. Field from localized static iron of approx. 200 Lbs. Field from moving iron objects of approx. 200 Lbs Metal chairs and doors Hand-carts and heavy metal doors Large moving objects (elevators and cars) Maximum floor vibrations below 1 Hz 20 Gauss 50 Gauss 50 Gauss 3 Gauss 6 to 10 Feet 10 to 15 Feet 20 to 40 Feet Approx. 0.1 mm Table 5: Stray field or distance from the magnet which may lead to noticeable instabilities Minimum field fluctuations (steps) Maximum ac fields (5 to 10 Hz range) Sweeping fields from mass spectrometers (with slow ramping up and no fly-back) Large switching DC currents (subway or trolley) 1 mgauss 5 to 10 mgauss 25 to 30 feet 500 to 1500 feet RECOMMENDATIONS FOR ROOM SELECTION We recommend locating the APEX TM III system at sufficient distance from large moving objects such as cars and elevators. Optimal locations are far away from internal and external traffic areas. For installation sites of high field magnets (7.0 and 9.4T) the rooms above and below the magnet must also be rather quiescent. We do not recommend locations in high rise buildings above the 5th floor because of vibration, sway, and atmospheric pressure fluctuations. The optimum site is in the basement or ground floor directly on the concrete slab. We also advise against locating high field systems in buildings near subway or train lines because of the high magnetic field instabilities caused by the passing of trains and DC currents. Floor support should be rigid in order to avoid vibrations. Windows should be located in such a way that sunlight does not shine directly on the dewar, and constructed such that no sudden pressure fluctuations are produced by winds. For optimal performance the room should be air conditioned with constant temperature control. Page 12 of 27

13 Inc. can provide site information and site inspections for your specific lab. Please contact your sales or service representative for more information and help in preparing the best possible site for your instrument MASS SPECTROMETER INSTALLATION RECEIVING Purchasers are notified at least seven days in advance of the proposed arrival date of the instrument, so that arrangements may be made to move it to the mass spectrometer room. In advance of shipment, contact the local Bruker office with any questions concerning installation of the instrument. It is assumed by Bruker that the instrument can be unloaded on a loading dock and pallet jacks are available at the customer site. If there is no standard height loading dock, Bruker has to be notified prior to shipment to make necessary arrangements. The console, vacuum system, magnet, and accessories will be separately crated allowing the use of a forklift truck to move the system to its final location. The customer has to make sure all hallways and doors from the loading area to the final position of the instrument are wide and high enough to move the magnet and vacuum cart through. The vacuum cart is 110cm (44 ) long and 127cm (50 ) wide, so a minimum door with of 130cm (51 ) is required on all doors. Some passively shielded magnets may require even wider doors; please refer to the magnet guide for dimensions. The minimum door height for most magnets is 7 feet (2.1m). Shipping crate dimensions: Vacuum cart ~1200lbs (140 x 175 x 175cm) Console: ~400lbs (85 x 95 x 140cm for U.S. or 155 x 95 x 160cm for international freight) Accessories: lbs (155 x 95 x 90cm) one or two boxes Magnet: refer to Magnet Guide Upon request, a Bruker representative will visit the customer site for an inspection. Page 13 of 27

14 4.2.0 GENERAL INSTALLATION PROCEDURE It is advisable to wait for arrival of the Bruker representative before any equipment is removed from the shipping crates. However, the crates may be placed near the system s final position. The utilities and cryogens should have been obtained. No attempt should be made to assemble or cool the magnet prior to the arrival of the field service engineer. It is advantageous to have at least one scientist or engineer who can spend most of his/her time working with the Bruker field service engineering during the installation. He/she will acquire valuable experience during this period as well as reduce the time of installation. During the installation, the personnel who are to be responsible for the operation and maintenance of the instrument should also be familiarizing themselves with the data system, circuits, manuals and as much of the instrument as possible LIFTING EQUIPMENT Assembly of the magnet system may be required. In all cases the facility must supply the necessary equipment to remove the magnet and vacuum cart from their shipping crates. The magnet system may require assembly onto a stand requiring lifting equipment, which can raise the magnet to the minimum ceiling height for your magnet. Other magnets (shielded Bruker-Magnex) may require assembly of the shielding. In this case the shields will have to be raised into position alongside the magnet. This usually requires a mobile hoist and the proper slings. For specific requirements for your system, please contact your local service office. Page 14 of 27

15 4.2.2 CRYOGENIC LIQUIDS The customer is responsible for up to the amounts of cryogen in the table in the following table. Total volume used may be less. Bruker offers a liquid helium plan, which provides all of the liquid helium needed for the cool down for a fixed price. Please contact your local sales representative or the magnet department for details and availability. Table 6: Cryogen Requirements Magnet LHe for installation (liters) LHe hold time (days) LHe refill volume (liters) N2 initial cooldown (liters) N2 hold time (days) Bruker/Magnex 3 T 160mm 300 > > N2 refill volume (liters) Bruker/Magnex 4.7T 160mm Actively Shielded Bruker/Magnex 7T 160mm Actively Shielded Bruker/Magnex 9.4 T 160mm Actively shielded 500 > > > > > > Note: All liquid nitrogen must be in low-pressure liquid withdrawal dewars (LX type). Converted gas packs cannot be used COOL DOWN EQUIPMENT The following items are also needed for the cool down of the magnet and must be supplied by the customer: One T cylinder of (industrial grade) nitrogen gas. One T cylinder of (industrial grade) helium gas. One low pressure gas regulator for inert gas (0-25 psi) Twenty feet of 3/8 inch Tygon tubing. Page 15 of 27

16 One Heat gun for de-icing and drying. Page 16 of 27

17 5.0.0 Appendix PRE-INSTALLATION CHECKLIST APEX TM II MASS SPECTROMETERS Space Requirements Installation Clearance around instrument Receiving Auxiliary equipment Handling the magnet Floor loading Personnel Required Ways from loading dock to Instrument location Electrician Utilities Environmental Filtered Soft Water Electrical power (380V 3-phase) Liquid nitrogen and helium Gas and Air Freezer for sample storage Air conditioning Electrical interference Magnetic Interference Vibration Dust and Corrosion Customer Signature / Date Bruker Representative Signature / Date Page 17 of 27

18 5.1.1 RECOMMENDED SITE LAYOUT for the APEX TM III The following figure shows the minimal room requirements for an APEX TM III FTMS system: All dimensions in mm *: Recommended place for all utility outlets (power, water, gases) For dimensions of other magnets please refer to the individual magnet specifications. Power Requirements: Three phase 380/220 V AC to neutral (+10%, -5%), 30 A, with ground (vacuum system and consoles) Single phase 110 or 220 V AC, 30/15A, (optional closed loop water chiller / LC / GC). Single phase 110 or 220 V AC, 20/10 A, quad outlet for computer and accessories Gas Requirements Dry, filtered dust and oil free; dew point below -40deg. F; psi regulated. Drying gas for the ESI source and Air for the pneumatic valves. Connected to a ¼ tubing each. Cooling Water Closed loop water chiller with at least 500W cooling capacity and 40psi pressure or 75 Liter/hour of filtered, soft house water that is not to exceed 20C. Page 18 of 27

19 Environmental Room temperature not to exceed 72deg. F. Total heat output of the system is around 4 kw (15,000-20,000 BTU/hr), depending on options minimum ceiling height: Passively shielded magnets: 3085mm, Actively shielded magnets: 3130mm, 9.4T AS magnet: 3300mm Magnet must be located as to be accessible for filling with cryogens. Page 19 of 27

20 5.1.2 Magnet Stray Fields 3T Passively Shielded Magnet Stray Field Page 20 of 27

21 4.7 T Actively Shielded Magnet Stray Field Page 21 of 27

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24 7 T Actively Shielded Magnet Stray Field Page 24 of 27

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26 9.4 T Actively Shielded Magnet Stray Field Page 26 of 27

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