Genomic DNA Enzymatic Labeling Kit Agilent Part Number X gdna Reaction Buffer Agilent Part Number

Transcription

1 Conforms to ANSI Z Standard (United States). Material Safety Data Sheet Genomic DNA Enzymatic Labeling Kit Product and company identification Product name Genomic DNA Enzymatic Labeling Kit Part No. Exo (-) Klenow X dntps Random Primer Not assigned. Not assigned. Manufacturer / Supplier Agilent Technologies, Inc. Logistics Center - Americas 500 Ships Landing Way New Castle, Delaware Emergency telephone number Use of the substance/preparation Validation date 10/01/ Physical state Hazards identification OSHA/HCS status Agilent (Information Telephone Number) Chemical Kit Liquid. Liquid. Liquid. Liquid. Liquid. Solid. Solid. This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR ). While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR ), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR ). While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR ), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR ), this MSDS contains valuable information critical to the safe Page 1/23

2 Genomic DNA Enzymatic Labeling Kit Hazards identification Emergency overview- Label Statement Routes of entry handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR ), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR ), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. MAY CAUSE RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS MATERIAL THAT MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA. CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS MATERIAL THAT MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA. NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. Contains material which may cause damage to the following organs kidneys, upper respiratory tract, skin, eye, lens or cornea. Contains material which may cause damage to the following organs skin. Eye contact. Ingestion. Dermal contact. Eye contact. Page 2/23

3 Genomic DNA Enzymatic Labeling Kit Hazards identification Potential acute health effects Eyes Skin Inhalation Ingestion Slightly irritating to the eyes. Irritating to eyes. Slightly irritating to the skin. Irritating to skin. Slightly irritating to the respiratory system. Irritating to respiratory system. Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure. Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure. Page 3/23

4 Genomic DNA Enzymatic Labeling Kit Hazards identification Medical conditions aggravated by overexposure Other adverse effects See toxicological information (section 11) 3. United States Repeated skin exposure can produce local skin destruction or dermatitis. Repeated or prolonged exposure to the substance can produce lung damage. Repeated or prolonged contact with spray or mist may produce chronic eye irritation and severe skin irritation. Repeated or prolonged exposure to the substance can produce target organs damage. Repeated skin exposure can produce local skin destruction or dermatitis. Repeated or prolonged exposure to the substance can produce lung damage. Repeated or prolonged contact with spray or mist may produce chronic eye irritation and severe skin irritation. Repeated or prolonged exposure to the substance can produce target organs damage. Composition/information on ingredients Name CAS number % Exo (-) Klenow Glycerol Water Exo (-) Klenow None assigned. 0.1 Water Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride Non-hazardous proprietary ingredients 8 10X dntps Water Deoxyribonucleic acids Edetic acid Random Primer Water Oligonucleotide None assigned. 0.3 Page 4/23

5 Genomic DNA Enzymatic Labeling Kit Composition/information on ingredients None assigned. 100 None assigned. 100 None assigned Eye contact Skin contact First aid measures In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if adverse health effects persist or are In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if adverse health effects persist or are In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if adverse health effects persist or are In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if adverse health effects persist or are In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if adverse health effects persist or are In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if adverse health effects persist or are In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if adverse health effects persist or are Wash with soap and water. Get medical attention if adverse health effects persist or are In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention if adverse health effects persist or are In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention if adverse health effects persist or are In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention if adverse health effects persist or are In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention if adverse health effects persist or are In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention if adverse health effects persist or are In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Page 5/23

6 Genomic DNA Enzymatic Labeling Kit Inhalation Ingestion First aid measures Get medical attention if adverse health effects persist or are If inhaled, remove to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention if adverse health effects persist or are If inhaled, remove to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention if adverse health effects persist or are If inhaled, remove to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention if adverse health effects persist or are If inhaled, remove to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention if adverse health effects persist or are If inhaled, remove to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention if adverse health effects persist or are If inhaled, remove to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention if adverse health effects persist or are If inhaled, remove to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Get medical attention if adverse health effects persist or are Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention if adverse health effects persist or are Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention if adverse health effects persist or are Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention if adverse health effects persist or are Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention if adverse health effects persist or are Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention if adverse health effects persist or are Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention if adverse health effects persist or are Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention if adverse health effects persist or are Page 6/23

7 Genomic DNA Enzymatic Labeling Kit First aid measures Protection of first-aiders Notes to physician In case of inhalation of decomposition products in a fire, symptoms may be delayed. The exposed person may need to be kept under medical surveillance for 48 hours. 5. Fire-fighting measures Flammability of the product Products of combustion Extinguishing media Suitable Non-flammable. Non-flammable. Non-flammable. Non-flammable. Non-flammable. Non-flammable. Non-flammable. Decomposition products may include the following materials carbon oxides Decomposition products may include the following materials carbon oxides nitrogen oxides halogenated compounds Decomposition products may include the following materials carbon oxides nitrogen oxides No specific data. No specific data. No specific data. No specific data. Use an extinguishing agent suitable for the surrounding fire. Use an extinguishing agent suitable for the surrounding fire. Use an extinguishing agent suitable for the surrounding fire. Use an extinguishing agent suitable for the surrounding fire. Use an extinguishing agent suitable for the surrounding fire. Page 7/23

8 Genomic DNA Enzymatic Labeling Kit Fire-fighting measures Use an extinguishing agent suitable for the surrounding fire. Use an extinguishing agent suitable for the surrounding fire. Not suitable Special protective equipment for fire-fighters Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode. 6. Accidental release measures Personal precautions No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Provide adequate Page 8/23

9 Genomic DNA Enzymatic Labeling Kit Accidental release measures ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). Environmental precautions Methods for cleaning up Small spill Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor. Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor. Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor. Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor. Stop leak if without risk. Move containers from spill area. Page 9/23

10 Genomic DNA Enzymatic Labeling Kit Handling Storage 8. Product name United States Accidental release measures Handling and storage Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor. Move containers from spill area. Vacuum or sweep up material and place in a designated, labeled waste container. Dispose of via a licensed waste disposal contractor. Move containers from spill area. Vacuum or sweep up material and place in a designated, labeled waste container. Dispose of via a licensed waste disposal contractor. Wash thoroughly after handling. Wash thoroughly after handling. Wash thoroughly after handling. Wash thoroughly after handling. Wash thoroughly after handling. Wash thoroughly after handling. Wash thoroughly after handling. Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination. Exposure controls/personal protection Exposure limits Exo (-) Klenow Glycerol ACGIH TLV (United States, 1/2007). TWA 10 mg/m³ 8 hour(s). Form Mist OSHA PEL (United States, 11/2006). TWA 5 mg/m³ 8 hour(s). Form Respirable fraction TWA 15 mg/m³ 8 hour(s). Form Total dust OSHA PEL 1989 (United States, 3/1989). TWA 5 mg/m³ 8 hour(s). Form Respirable fraction TWA 10 mg/m³ 8 hour(s). Form Total dust Consult local authorities for acceptable exposure limits. Engineering measures Hygiene measures Personal protection If user operations generate dust, fumes, gas, vapor or mist, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits. Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location. Page 10/23

11 Genomic DNA Enzymatic Labeling Kit Eyes Skin Respiratory Exposure controls/personal protection Hands Other protection 9. Physical state ph Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. Chemical resistant protective gloves and clothing are recommended. The choice of protective gloves or clothing must be based on chemical resistance and other use requirements. Generally, BUNA-N offers acceptable chemical resistance. Individuals who are acutely and specifically sensitive to this chemical may require additional protective clothing. Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. Physical and chemical properties Boiling/condensation point Liquid. Liquid. Liquid. Liquid. Liquid. Solid. Solid. Neutral. 6.8 [Neutral.] Lowest known value 100 C (212 F) (Water). Weighted average C (383.2 F) Lowest known value 100 C (212 F) (Water). Lowest known value 100 C (212 F) (Water). Lowest known value 100 C (212 F) (Water). Page 11/23

12 Genomic DNA Enzymatic Labeling Kit Physical and chemical properties Melting/freezing point Vapor pressure Vapor density 10. Stability and reactivity Stability and reactivity Incompatibility with various substances Hazardous decomposition products May start to solidify at the following temperature 19.8 C (67.6 F) This is based on data for the following ingredient Glycerol. Weighted average 9.91 C (49.8 F) May start to solidify at the following temperature 0 C (32 F) This is based on data for the following ingredient Water. May start to solidify at the following temperature 0 C (32 F) This is based on data for the following ingredient Water. May start to solidify at the following temperature 0 C (32 F) This is based on data for the following ingredient Water. Highest known value 2.3 kpa (17.5 mm Hg) (at 20 C) (Water). Highest known value 2.3 kpa (17.5 mm Hg) (at 20 C) (Water). Highest known value 2.3 kpa (17.5 mm Hg) (at 20 C) (Water). Highest known value 2.3 kpa (17.5 mm Hg) (at 20 C) (Water). Highest known value 3.1 (Air = 1) (Glycerol). Weighted average 1.86 (Air = 1) Highest known value 0.62 (Air = 1) (Water). Highest known value 0.62 (Air = 1) (Water). Highest known value 0.62 (Air = 1) (Water). The product is stable. Under normal conditions of storage and use, hazardous polymerization will not occur. Slightly reactive or incompatible with the following materials oxidizing materials and metals. Under normal conditions of storage and use, hazardous decomposition products should not be produced. Under normal conditions of storage and use, hazardous decomposition products should not be produced. Under normal conditions of storage and use, hazardous decomposition products should not be produced. Under normal conditions of storage and use, hazardous decomposition products should not be produced. Page 12/23

13 Genomic DNA Enzymatic Labeling Kit Stability and reactivity Toxicological information Acute toxicity Under normal conditions of storage and use, hazardous decomposition products should not be produced. Under normal conditions of storage and use, hazardous decomposition products should not be produced. Under normal conditions of storage and use, hazardous decomposition products should not be produced. Product/ingredient name Result Species Dose Exposure Glycerol LD50 Oral Rat mg/kg - Eyes Skin Inhalation Slightly irritating to the eyes. Irritating to eyes. Slightly irritating to the skin. Irritating to skin. Slightly irritating to the respiratory system. Irritating to respiratory system. Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure. Exposure to decomposition products may cause a health hazard. Serious effects may be delayed following exposure. Page 13/23

14 Genomic DNA Enzymatic Labeling Kit Ingestion Toxicological information Potential chronic health effects Chronic effects Carcinogenicity Mutagenicity Teratogenicity Developmental effects Fertility effects Contains material that may cause target organ damage, based on animal data. Over-exposure signs/symptoms Inhalation Adverse symptoms may include the following respiratory tract irritation coughing Ingestion No specific data. Skin Adverse symptoms may include the following irritation redness Eyes Target organs Other adverse effects Adverse symptoms may include the following pain or irritation watering redness Contains material which may cause damage to the following organs kidneys, upper respiratory tract, skin, eye, lens or cornea. Contains material which may cause damage to the following organs skin. Page 14/23

15 Genomic DNA Enzymatic Labeling Kit Toxicological information Ecological information Environmental effects Aquatic ecotoxicity Product/ingredient name Test Result Species Glycerol - Acute LC50 54 to 57 ml/l Fresh water Fish Other adverse effects 13. Disposal considerations Waste disposal Exposure 96 hours The generation of waste should be avoided or minimized wherever possible. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Disposal should be in accordance with applicable regional, national and local laws and regulations. Local regulations may be more stringent than regional or national requirements. The information presented below only applies to the material as supplied. The identification based on characteristic(s) or listing may not apply if the material has been used or otherwise contaminated. It is the responsibility of the waste generator to determine the toxicity and physical properties of the material generated to determine the proper waste identification and disposal methods in compliance with applicable regulations. Refer to Section 7 HANDLING AND STORAGE and Section 8 EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees. 14. Transport information Regulatory information TDG/ DOT / IMDG / IATA Not regulated. 15. Regulatory information United States HCS Classification Part Number Agilent Part Number 10X dntps Part Number Agilent Part Number Target organ effects Not regulated. Target organ effects Not regulated. Not regulated. Not regulated. Not regulated. Page 15/23

16 Genomic DNA Enzymatic Labeling Kit Regulatory information U.S. Federal regulations Part Number Agilent Part Number 10X dntps Part Number Agilent Part Number Part Number Agilent Part Number 10X dntps Part Number Contains material which may cause damage to the following organs kidneys, upper respiratory tract, skin, eye, lens or cornea. Contains material which may cause damage to the following organs skin. United States inventory (TSCA 8b) At least one component is not United States inventory (TSCA 8b) At least one component is not United States inventory (TSCA 8b) At least one component is not United States inventory (TSCA 8b) At least one component is not United States inventory (TSCA 8b) At least one component is not United States inventory (TSCA 8b) This material is not United States inventory (TSCA 8b) This material is not SARA 302/304/311/312 extremely hazardous SARA 302/304 emergency planning and notification No products were SARA 302/304/311/312 hazardous chemicals Glycerol SARA 311/312 MSDS distribution - chemical inventory - hazard identification Glycerol Immediate (acute) health hazard, Delayed (chronic) health hazard SARA 302/304/311/312 extremely hazardous SARA 302/304 emergency planning and notification No products were SARA 302/304/311/312 hazardous chemicals No products were SARA 311/312 MSDS distribution - chemical inventory - hazard identification No products were SARA 302/304/311/312 extremely hazardous SARA 302/304 emergency planning and notification No products were SARA 302/304/311/312 hazardous chemicals Edetic acid SARA 311/312 MSDS distribution - chemical inventory - hazard identification Edetic acid Immediate (acute) health hazard, Delayed (chronic) health hazard SARA 302/304/311/312 extremely hazardous Page 16/23

17 Genomic DNA Enzymatic Labeling Kit Regulatory information Agilent Part Number SARA 302/304 emergency planning and notification No products were SARA 302/304/311/312 hazardous chemicals No products were SARA 311/312 MSDS distribution - chemical inventory - hazard identification No products were SARA 302/304/311/312 extremely hazardous SARA 302/304 emergency planning and notification No products were SARA 302/304/311/312 hazardous chemicals No products were SARA 311/312 MSDS distribution - chemical inventory - hazard identification No products were SARA 302/304/311/312 extremely hazardous SARA 302/304 emergency planning and notification No products were SARA 302/304/311/312 hazardous chemicals No products were SARA 311/312 MSDS distribution - chemical inventory - hazard identification No products were SARA 302/304/311/312 extremely hazardous SARA 302/304 emergency planning and notification No products were SARA 302/304/311/312 hazardous chemicals No products were SARA 311/312 MSDS distribution - chemical inventory - hazard identification No products were Part Number Agilent Part Number 10X dntps Part Number Agilent Part Number Part Number Agilent Part Number 10X dntps Part Number Agilent Part Number Clean Water Act (CWA) 307 No products were Clean Water Act (CWA) 307 No products were Clean Water Act (CWA) 307 No products were Clean Water Act (CWA) 307 No products were Clean Water Act (CWA) 307 No products were Clean Water Act (CWA) 307 No products were Clean Water Act (CWA) 307 No products were Clean Water Act (CWA) 311 No products were Clean Water Act (CWA) 311 No products were Clean Water Act (CWA) 311 Edetic acid Clean Water Act (CWA) 311 No products were Clean Water Act (CWA) 311 No products were Page 17/23

18 Genomic DNA Enzymatic Labeling Kit Regulatory information Part Number Agilent Part Number 10X dntps Part Number Agilent Part Number Part Number Agilent Part Number 10X dntps Part Number Agilent Part Number Clean Water Act (CWA) 311 No products were Clean Water Act (CWA) 311 No products were Clean Air Act (CAA) 112 accidental release prevention No products were Clean Air Act (CAA) 112 accidental release prevention No products were Clean Air Act (CAA) 112 accidental release prevention No products were Clean Air Act (CAA) 112 accidental release prevention No products were Clean Air Act (CAA) 112 accidental release prevention No products were Clean Air Act (CAA) 112 accidental release prevention No products were Clean Air Act (CAA) 112 accidental release prevention No products were Clean Air Act (CAA) 112 regulated flammable Clean Air Act (CAA) 112 regulated flammable Clean Air Act (CAA) 112 regulated flammable Clean Air Act (CAA) 112 regulated flammable Clean Air Act (CAA) 112 regulated flammable Clean Air Act (CAA) 112 regulated flammable Clean Air Act (CAA) 112 regulated flammable State regulations Part Number Agilent Part Number 10X dntps Part Number Agilent Part Number Part Number Clean Air Act (CAA) 112 regulated toxic Clean Air Act (CAA) 112 regulated toxic Clean Air Act (CAA) 112 regulated toxic Clean Air Act (CAA) 112 regulated toxic Clean Air Act (CAA) 112 regulated toxic Clean Air Act (CAA) 112 regulated toxic Clean Air Act (CAA) 112 regulated toxic Connecticut Carcinogen Reporting None of the components are Connecticut Hazardous Material Survey None of the components are Florida substances None of the components are Illinois Chemical Safety Act None of the components are Illinois Toxic Substances Disclosure to Employee Act None of the components are Louisiana Reporting None of the components are Page 18/23

19 Genomic DNA Enzymatic Labeling Kit Regulatory information Agilent Part Number 10X dntps Louisiana Spill None of the components are Massachusetts Spill None of the components are Massachusetts Substances The following components are listed Glycerol Michigan Critical Material None of the components are Minnesota Hazardous Substances None of the components are New Jersey Hazardous Substances None of the components are New Jersey Spill None of the components are New Jersey Toxic Catastrophe Prevention Act None of the components are New York Acutely Hazardous Substances None of the components are New York Toxic Chemical Release Reporting None of the components are Pennsylvania RTK Hazardous Substances The following components are listed Glycerol Rhode Island Hazardous Substances None of the components are Connecticut Carcinogen Reporting None of the components are Connecticut Hazardous Material Survey None of the components are Florida substances None of the components are Illinois Chemical Safety Act None of the components are Illinois Toxic Substances Disclosure to Employee Act None of the components are Louisiana Reporting None of the components are Louisiana Spill None of the components are Massachusetts Spill None of the components are Massachusetts Substances None of the components are Michigan Critical Material None of the components are Minnesota Hazardous Substances None of the components are New Jersey Hazardous Substances None of the components are New Jersey Spill None of the components are New Jersey Toxic Catastrophe Prevention Act None of the components are New York Acutely Hazardous Substances None of the components are New York Toxic Chemical Release Reporting None of the components are Pennsylvania RTK Hazardous Substances None of the components are Rhode Island Hazardous Substances None of the components are Connecticut Carcinogen Reporting None of the Page 19/23

20 Genomic DNA Enzymatic Labeling Kit Regulatory information components are Connecticut Hazardous Material Survey None of the components are Florida substances None of the components are Illinois Chemical Safety Act None of the components are Illinois Toxic Substances Disclosure to Employee Act None of the components are Louisiana Reporting None of the components are Louisiana Spill None of the components are Massachusetts Spill None of the components are Massachusetts Substances The following components are listed Edetic acid Michigan Critical Material None of the components are Minnesota Hazardous Substances None of the components are New Jersey Hazardous Substances The following components are listed Edetic acid New Jersey Spill None of the components are New Jersey Toxic Catastrophe Prevention Act None of the components are New York Acutely Hazardous Substances The following components are listed Edetic acid New York Toxic Chemical Release Reporting None of the components are Pennsylvania RTK Hazardous Substances The following components are listed Edetic acid Rhode Island Hazardous Substances None of the components are Part Number Connecticut Carcinogen Reporting None of the components are Connecticut Hazardous Material Survey None of the components are Florida substances None of the components are Illinois Chemical Safety Act None of the components are Illinois Toxic Substances Disclosure to Employee Act None of the components are Louisiana Reporting None of the components are Louisiana Spill None of the components are Massachusetts Spill None of the components are Massachusetts Substances None of the components are Michigan Critical Material None of the components are Minnesota Hazardous Substances None of the components are New Jersey Hazardous Substances None of the components are New Jersey Spill None of the components are New Jersey Toxic Catastrophe Prevention Act Page 20/23

21 Genomic DNA Enzymatic Labeling Kit Regulatory information Agilent Part Number None of the components are New York Acutely Hazardous Substances None of the components are New York Toxic Chemical Release Reporting None of the components are Pennsylvania RTK Hazardous Substances None of the components are Rhode Island Hazardous Substances None of the components are Connecticut Carcinogen Reporting None of the components are Connecticut Hazardous Material Survey None of the components are Florida substances None of the components are Illinois Chemical Safety Act None of the components are Illinois Toxic Substances Disclosure to Employee Act None of the components are Louisiana Reporting None of the components are Louisiana Spill None of the components are Massachusetts Spill None of the components are Massachusetts Substances None of the components are Michigan Critical Material None of the components are Minnesota Hazardous Substances None of the components are New Jersey Hazardous Substances None of the components are New Jersey Spill None of the components are New Jersey Toxic Catastrophe Prevention Act None of the components are New York Acutely Hazardous Substances None of the components are New York Toxic Chemical Release Reporting None of the components are Pennsylvania RTK Hazardous Substances None of the components are Rhode Island Hazardous Substances None of the components are Connecticut Carcinogen Reporting This material is not Connecticut Hazardous Material Survey This material is not Florida substances This material is not Illinois Chemical Safety Act This material is not Illinois Toxic Substances Disclosure to Employee Act This material is not Louisiana Reporting This material is not Louisiana Spill This material is not Massachusetts Spill This material is not Massachusetts Substances This material is not Michigan Critical Material This material is not Minnesota Hazardous Substances This material Page 21/23

22 Genomic DNA Enzymatic Labeling Kit Regulatory information is not New Jersey Hazardous Substances This material is not New Jersey Spill This material is not New Jersey Toxic Catastrophe Prevention Act This material is not New York Acutely Hazardous Substances This material is not New York Toxic Chemical Release Reporting This material is not Pennsylvania RTK Hazardous Substances This material is not Rhode Island Hazardous Substances This material is not Connecticut Carcinogen Reporting This material is not Connecticut Hazardous Material Survey This material is not Florida substances This material is not Illinois Chemical Safety Act This material is not Illinois Toxic Substances Disclosure to Employee Act This material is not Louisiana Reporting This material is not Louisiana Spill This material is not Massachusetts Spill This material is not Massachusetts Substances This material is not Michigan Critical Material This material is not Minnesota Hazardous Substances This material is not New Jersey Hazardous Substances This material is not New Jersey Spill This material is not New Jersey Toxic Catastrophe Prevention Act This material is not New York Acutely Hazardous Substances This material is not New York Toxic Chemical Release Reporting This material is not Pennsylvania RTK Hazardous Substances This material is not Rhode Island Hazardous Substances This material is not State regulations - California Prop Other information Label requirements No products were MAY CAUSE RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS MATERIAL THAT MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA. CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS MATERIAL THAT MAY CAUSE TARGET ORGAN DAMAGE, BASED ON ANIMAL DATA. NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE Page 22/23

23 Genomic DNA Enzymatic Labeling Kit Other information HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. Date of issue 10/01/2009 Date of previous issue 11/27/2008 Version 2 Notice to reader DISCLAIMER This Material Safety Data Sheet is offered without charge to the clients of Agilent Technologies. Data is the most current available to Agilent Technologies at the time of preparation and is issued as a matter of information only, no warranty as to its accuracy or completeness is expressed or implied. Page 23/23