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1 Female Jockey Wins Melbourne Cup on KIWI HORSE
2 Research in CICO Transtracheal jet oxygenation and ventilation Colin Marsland ANZCA NZ ASM Wellington 2015
3 Experimental Airway Obstruction, TTJV and Fatality Neff et al J Trauma 1983;23:84-90 Paxian et al BJA 2015;115: Constant Flow 15L/min via 15G cannula Paw 260cm H2O at 15 sec Death at 18 sec Intermittent Jets 15L/min 3:5 sec I:E Paw 254cm H2O at 64 sec Death at 65 sec Intermittent jets 0.5 bar manujet 1:4 sec I:E Paw 50cm H2O for 6 min 30% mortality in pigs
4 Whale Sharks and WAAG
5 Manujet Complete Obstruction
6 Physiology in Play V/Q, V/P, O 2 Shunt Lung Compliance O2 transport Physiologic Dead Space Auto-PEEP
7 Berry M, Tzeng Y, Marsland C Percutaneous transtracheal ventilation in an obstructed airway model in post-apnoeic sheep. Br J Anaesth 2014;113:
8 Manujet vs Ventrain Pressure regulated 0-4 bar 50 psi O 2 source 250ml O 2 sec -1 2mm TTC 1 bar Manual operation No automatic shut off Flow regulated, EVA 15Lmin -1 O 2 flowmeter 250ml O 2 sec -1 2mm TTC Manual operation Triphasic ventilation
9 Ventrain (manufacturer s graphic) INSP EXP EQ
10 Ventrain Complete Obstruction
11 Manujet Complete Obstruction 5 minute oxygenation window after single breath Median time to secondary breath 7m20s
12 SaO 2 and Airway Pressure VO Ventrain Obstructed VP Ventrain Partial Obstruction MO Manujet Obstructed MP Manujet Partial Obstruction
13 Table of Results
14 Ventrain The ideal device for TTJV?? INSP EXP NO. TOO COMPLICATED FOR CRISIS USE EQUIL
15 Rapid-O 2 Concept developed by A.Heard et al RPH Flow regulated 15L/min delivers 250ml/sec O2 via 14G TTC No flow to TTC if T not occluded Feedback at occlusion site Passive expiration Simple, Cheap, Effective
16 Proximal Leak and TTJO
17 Big Proximal Leak and TTJO
18 CICO Kits in Wgtn
19 Local Training Heard Algorithm Dry Lab Skills Simulation Anaesthetised Sheep Initial Emphasis Senior staff and Technicians Trainees
20 Whale Sharks and WAAG with credit to Dr A.Heard et al
21 CICO Emphasis Oxygenation not Ventilation Temporising oxygenation to allow definitive airway management Minimize barotrauma risk with minimal breath frequency (peak sat falls 5% = trigger) Hypercarbia not the issue in the short term
22 Cannula Indicated?? Cannulation improbable: Non-palpable anatomy No end-point e.g blood or vomit on aspiration PTO ineffective/dangerous: Big leak e.g perforated airway Barotrauma Lung injury
23 Scalpel Best First Choice Environment Military/Field Crises/Specialty culture Airway trauma / Barotrauma Low lung compliance Lung injury, soiling with blood / vomit Anatomy
24 Pre-emptive Ultrasound CTM Correct ID of CTM by palpation in Obese patients: <10% ID BMI >30 Aslani et al Anesth Analg 2012;114: Time to ID CTM with USS 30 seconds Nicholls et al Am J Emerg Med 2008;26:852-6 Portex Kit in cadavers with difficult or impalpable landmarks: Success: 8% vs 46% with USS Moderate to severe injury:100% vs 33% with USS Siddiqui et al Anesthesiology 2015;123:
25 Questions?
26 Examine Front of Neck in Potentially Difficult Airways Consider pre-emptive USS definition of CTM and trachea if anatomy is impalpable
27 Simulated Obesity and Burn Howes et al BJA 2015;114:1:136-42
28 Complete Airway Obstruction in CICO Good Bad Lung inflation with flowcontrolled devices Auto-PEEP maintains lung volume Breath Stacking Barotrauma Pulmonary flow impairment
29 Large Proximal Leak and PTV Bad Good Lung inflation difficult with flow-controlled devices No PEEP to maintain lung volume Unimpeded gas egress Minimal Barotrauma Risk Low intra-thoracic pressure
30 Oxygenate Safely Minimise Ventilation in CICO Paxian et al BJA 2015;115:2: % mortality (pigs) with fixed ventilation, complete obstruction and Manujet
31 Emergency PTV TC position confirmed - long axis tracheal lumen High pressure O2 source - cannula resistance Proximal airway obstruction - gas egress lung inflation limited if escapes too much barotrauma if escapes too little minute ventilation affected with each
32 Hypothesis Post-apnoeic transtracheal oxygenation with critical and complete proximal airway obstruction will be achievable with both Ventrain and Manujet devices, but airway pressures lower with Ventrain. Test Compare primary outcome measures (oxygenation, airway pressure and CO 2 clearance) following PTV in a large animal obstructed airway model.
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