Noticias News Nouvelles

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Noticias News Nouvelles The Centre for Mother, Infant, and Child Research Sunnybrook Health Sciences Centre C8-2075 Bayview Avenue, Toronto ON CANADA M4N 3M5 Tel: 1 416 480 5639 Fax: 1 416 480 5633

! 1 Final Analysis 2 Reminder: 2 year follow-up 2 Total in February: 43 Recruitment Countdown We have less than 50 recruits left to reach our recruitment goal!

1 Noticias News Nouvelles The Centre for Mother, Infant, and Child Research Sunnybrook Health Sciences Centre C Bayview Avenue, Toronto ON CANADA M4N 3M5 Tel: Fax: tbs@sw.ca website: V O L U M E 1 0, I S S U E 2 F E B R U A R Y 2 8, Overall Total: 2757 I N S I D E T H I S I S S U E Recruitment Countdown WE ARE NEAR THE END!! 1 Final Analysis 2 Reminder: 2 year follow-up 2 Total in February: 43 Recruitment Countdown We have less than 50 recruits left to reach our recruitment goal!! Congratulations to everyone for a strong recruitment month in February! At this rate, we have less than two months to go. Recruit a patient today! Below, our babies are nearly at the finish line! Query Tutorial 3 Recruitment Excellence 4 Recruitment Table 5 2yr Table 8

P A G E 2 The Data Campaign is underway! FINAL ANALYSIS The Final Analysis is planned for later this year. In order to carry out the analysis, WE NEED YOUR HELP!

2 P A G E 2 The Data Campaign is underway! FINAL ANALYSIS The Final Analysis is planned for later this year. In order to carry out the analysis, WE NEED YOUR HELP! Please send all outstanding data, unanswered queries, and overdue supporting documents, to the Data Coordinating Centre as soon as possible! WE ARE ALMOST THERE! PLEASE SEND US YOUR DATA TODAY! Reminder: 2 year follow-up Recently, much of the excitement and focus has been on recruitment and returning the primary data. However, it is also important to remember the importance of our secondary outcome: the 2 year follow-up. To help you keep organized, please use the Follow-up Reminders provided by the Data Coordinating Centre. Tips for success: Maintain contact with your patients every 3 months Know when the 2-year follow-up is due for each of your patients Ensure your patients complete the ASQ within the valid window If applicable, complete the Neurodevelopmental Assessment form as soon as possible For details on the process or for more tips, please refer to your TBS Manual. Let s aim for 100% folow-up!

3 P A G E 3 Query tutorial Labour Form, Question 17: Listing Clinician Codes If a Clinician Code has been entered here, STOP here. 0 2 If a Clinician Code was entered above, do not complete the section below. The section: description of delivering obstetrician(s) should be left blank.

4 P A G E 4 Recruitment Excellence Congratulations to Dr Elsa Andina and the team at Hospital Sarda, Buenos Aires, Argentina; Dr Carlos Arias and the team at Hospital JM Cullen, Santa Fe, Argentina; Dr George Carson and the team at Regina General Hospital, Regina, Canada; Dr Steven Kaye and the team at Lion s Gate Hospital, Vancouver, Canada; Dr Marwan Hakim and the team at Nazareth Hospital (EMMS), Nazareth, Israel; Dr Dalia Mansour-Schwake and the team at Holy Family Hospital, Nazareth, Israel; and Dr Elena Carreras Moratonas and the team at Hospital Val d Hebron, Barcelona, Spain. Keep up the excellent work! We will be sending a gold seal to place on your Certificate of Achievement. "Desire is the key to motivation, but it's the determination and commitment to an unrelenting pursuit of your goal - a commitment to excellence - that will enable you to attain the success you seek." ~Mario Andretti (race car driver)

5 P A G E 5 Twin Birth Study Recruitment (Projected sample size of 2800) February 28, 2011 Annual Jun Jul - Nov Jan Feb Grand Goal Total COUNTRY ARGENTINA BRAZIL CANADA ISRAEL POLAND UK CHILE SPAIN EGYPT AUSTRALIA THE NETHERLANDS SERBIA USA JORDAN ESTONIA JAMAICA QATAR HUNGARY OMAN ROMANIA BELGIUM GERMANY URUGUAY CROATIA GREECE Total CENTRES BY COUNTRY (Shaded area is prior to start-up) ARGENTINA Hospital LC Lagomaggiore, Mendoza Hospital Ramon Carrillo, Santiago del Estero Hospital Posadas, Buenos Aires Hospital Avellaneda, Tucuman Hospital JR Vidal, Corrientes Hospital Penna, Bahia Blanca Hospital Sarda, Buenos Aires Hospital Angela Iglesia de Llano, Corrientes Hospital Juan A Fernandez, Buenos Aires Hospital Alvarez, Buenos Aires Hospital JM Cullen, Santa Fe Centre(s) that are no longer recruiting 0 10 BRAZIL Maternidade Escola da UFRJ, Rio de Janeiro University of Campinas, Campinas University of Pernambuco, Recife Maternidade Escola de Vila Nova Cachoeirinha, Sao Paulo Hospital Universitario de Jundiai, Jundiai Hospital Sao Lucas, Porto Alegre Hospital Universitario Antonio Pedro, Niteroi Perinatal, Rio de Janeiro ISCMPA-Maternidade Mario Totta, Porto Alegre Botucatu Medical School, Botucatu Hospital Materno Infantil, Goiania Hospital das Clinicas da UFPE, Recife Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife 8 1 1

6 P A G E 6 Annual Jun Jul - Nov Jan Feb Grand Goal Total CANADA Sunnybrook Health Sciences Centre, Toronto IWK Health Centre, Halifax Regina General Hospital, Regina Trillium Health Centre, Mississauga Lion's Gate Hospital, Vancouver Foothills Medical Centre, Calgary St Joseph's Health Care, London SMBD Jewish General Hospital, Montreal North Bay General Hospital, North Bay Royal Columbian Hospital, New Westminster Royal University Hospital, Saskatoon Toronto East General, Toronto Women s Health Centre, St John's Children's & Women's Health Centre of BC, Vancouver St Paul's Hospital, Vancouver Centre(s) that are no longer recruiting 0 36 ISRAEL Nazareth Hospital (EMMS), Nazareth Ma'ayney HaYeshua Medical Center, Bnei Brak Edith Wolfson Medical Center, Holon Holy Family Hospital, Nazareth HaEmek Medical Center, Afula Poriya Government Hospital, Tiberias Hillel Yaffe Medical Center, Hadera Bnai Zion Medical Center, Haifa POLAND University School of Medical Sciences, Poznan Polish Mother's Memorial Hospital, Lodz Medical University of Gdansk, Gdansk UK Bradford Royal Infirmary, Bradford Nottingham City Hospital, Nottingham Basildon & Thurrock University Hospital, Basildon Liverpool Women's Hospital, Liverpool Derriford Hospital, Plymouth Queen's Medical Centre, Nottingham Queen Elizabeth Hospital, King's Lynn University Hospital of North Staffordshire, Stoke-on-Trent City Hospitals Sunderland NHS Foundation Trust, Sunderland Lewisham Hospital, London CHILE Hospital Dr Gustavo Fricke, Vina del Mar Hospital Dr Sotero del Rio, Puente Alto SPAIN Hospital Clinic-University of Barcelona, Barcelona Hospital La Paz, Madrid Hospital Vall d'hebron, Barcelona Complejo Hospitalario de Toledo, Toledo EGYPT Assiut University Hospital, Assiut AUSTRALIA Ipswich Hospital, Ipswich Mater Mothers' Hospital, Brisbane St George Hospital, Sydney Toowoomba Base Hospital, Toowoomba Monash Medical Centre, Clayton Logan Hospital, Meadowbrook Women's and Children's Hospital, Adelaide Townsville Hospital, Townsville

7 P A G E 7 Annual Jun Jul - Nov Jan Feb Grand Goal Total THE NETHERLANDS Atrium Medical Center, Heerlen Academisch Ziekenhuis Maastricht, Maastricht Maxima Medical Centre, Veldhoven Sint Lucas Andreas Ziekenhuis, Amsterdam Centre(s) that are no longer recruiting 0 7 SERBIA University of Belgrade, Belgrade USA East Bay Perinatal Medical Associates, Oakland Maricopa Medical Center, Phoenix University of Miami, Miami University of South Carolina, Columbia University of Iowa Hospitals and Clinics, Iowa City Centre(s) that are no longer recruiting 0 4 JORDAN Islamic Hospital, Amman ESTONIA Tartu University Hospital - Women's Clinic, Tartu JAMAICA University Hospital of the West Indies, Kingston QATAR Hamad Medical Corporation, Doha HUNGARY University of Debrecen, Debrecen OMAN Khoula Hospital, Muscat ROMANIA University of Pharmacy and Medicine, Cluj-Napoca GERMANY Ludwig Maximilians University of Munich, Munich CUB - Virchow Klinikum, Berlin CUB - Benjamin Franklin, Berlin BELGIUM Centre(s) that are no longer recruiting 0 15 URUGUAY Pereira Rossell Hospital, Montevideo CROATIA Centre(s) that are no longer recruiting 0 9 GREECE Centre(s) that are no longer recruiting 0 4 Centres awaiting first patient: [COUNTRY: Hospital, City (annual goal)] [month/year start-up package sent] UK: Aberdeen Maternity, Aberdeen (6) [11/06];

8 P A G E 8 TBS 2 Year Follow-up The status of the TBS 2 Year Follow-up is displayed in the following table for centres that recruited patients. Centres are listed according to the total number of recruits by country and centre. See below for the number of follow-up assessments performed by your centre! Let's aim for 100% follow-up!! Status Totals As of February 2011 COUNTRY ARGENTINA BRAZIL CANADA ISRAEL POLAND UK CHILE SPAIN EGYPT AUSTRALIA THE NETHERLANDS SERBIA USA JORDAN ESTONIA JAMAICA QATAR HUNGARY OMAN ROMANIA GERMANY BELGIUM URUGUAY CROATIA GREECE Total % 91.8% 87.7% 83.4% 82.1% 66.1% 2.1% 50% CENTRES BY COUNTRY (Shaded area is prior to start-up) ARGENTINA Hospital LC Lagomaggiore, Mendoza Hospital Ramon Carrillo, Santiago del Estero Hospital Posadas, Buenos Aires Hospital Avellaneda, Tucuman Hospital JR Vidal, Corrientes Hospital Sarda, Buenos Aires Hospital Penna, Bahia Blanca Hospital Angela Iglesia de Llano, Corrientes Hospital Juan A Fernandez, Buenos Aires Hospital Ramos Mejia, Buenos Aires Hospital Alvarez, Buenos Aires Hospital JM Cullen, Santa Fe BRAZIL Maternidade Escola da UFRJ, Rio de Janeiro University of Campinas, Campinas University of Pernambuco, Recife Maternidade Escola de Vila Nova Cachoeirinha, Sao Paulo Hospital Universitario de Jundiai, Jundiai Hospital Sao Lucas, Porto Alegre Hospital Universitario Antonio Pedro, Niteroi Perinatal, Rio de Janeiro ISCMPA-Maternidade Mario Totta, Porto Alegre Botucatu Medical School, Botucatu Hospital Materno Infantil, Goiania Hospital das Clinicas da UFPE, Recife Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife 1 1 CANADA Sunnybrook Health Sciences Centre, Toronto IWK Health Centre, Halifax McMaster University Medical Centre, Hamilton Regina General Hospital, Regina Trillium Health Centre, Mississauga Lion's Gate Hospital, Vancouver Mount Sinai Hospital, Toronto Foothills Medical Centre, Calgary St Joseph's Health Care, London SMBD Jewish General Hospital, Montreal Royal Columbian Hospital, New Westminster Royal University Hospital, Saskatoon North Bay General Hospital, North Bay Toronto East General, Toronto Women s Health Centre, St John's York Central Hospital, Richmond Hill 1 1 Children's & Women's Health Centre of BC, Vancouver 1 1 St Paul's Hospital, Vancouver 1 1 ISRAEL Nazareth Hospital (EMMS), Nazareth Ma'ayney HaYeshua Medical Center, Bnei Brak Edith Wolfson Medical Center, Holon Holy Family Hospital, Nazareth HaEmek Medical Center, Afula Poriya Government Hospital, Tiberias Hillel Yaffe Medical Center, Hadera Bnai Zion Medical Center, Haifa

9 P A G E 9 Status Totals As of February 2011 POLAND Univ School of Medicine, Poznan Polish Mother's Memorial Hospital, Lodz Medical University of Gdansk, Gdansk UK Bradford Royal Infirmary, Bradford Nottingham City Hospital, Nottingham Basildon & Thurrock University Hospital, Basildon Liverpool Women's Hospital, Liverpool Derriford Hospital, Plymouth Queen's Medical Centre, Nottingham Queen Elizabeth Hospital, King's Lynn University Hospital of North Staffordshire, Stoke-on-Trent City Hospitals Sunderland NHS Foundation Trust, Sunderland Lewisham Hospital, London 3 3 CHILE Hospital Dr Gustavo Fricke, Vina del Mar Hospital Dr Sotero del Rio, Puente Alto SPAIN Hospital Clinic-University of Barcelona, Barcelona Hospital La Paz, Madrid Hospital Vall d'hebron, Barcelona Complejo Hospitalario de Toledo, Toledo EGYPT Assiut University Hospital, Assiut AUSTRALIA Ipswich Hospital, Ipswich Mater Mothers' Hospital, Brisbane St George Hospital, Sydney Toowoomba Base Hospital, Toowoomba Monash Medical Centre, Clayton Logan Hospital, Meadowbrook Women's and Children's Hospital, Adelaide Townsville Hospital, Townsville THE NETHERLANDS Atrium Medical Center, Heerlen Academisch Ziekenhuis Maastricht, Maastricht Maxima Medical Centre, Veldhoven Maaslandziekenhuis Sittard, Sittard Sint Lucas Andreas Ziekenhuis, Amsterdam SERBIA University of Belgrade, Belgrade USA East Bay Perinatal Medical Associates, Oakland Maricopa Medical Center, Phoenix University of Miami, Miami University of South Carolina, Columbia Jamaica Hospital Medical Center, Jamaica Texas Tech UHSC, Lubbock 2 2 University of Iowa Hospitals and Clinics, Iowa City JORDAN Islamic Hospital, Amman ESTONIA Tartu University Hospital - Women's Clinic, Tartu JAMAICA University Hospital of the West Indies, Kingston QATAR Hamad Medical Corporation, Doha HUNGARY University of Debrecen, Debrecen OMAN Khoula Hospital, Muscat ROMANIA University of Pharmacy and Medicine, Cluj-Napoca GERMANY Ludwig Maximilians University of Munich, Munich CUB - Virchow Klinikum, Berlin 3 3 CUB - Benjamin Franklin, Berlin BELGIUM Vrije Universiteit Brussel, Brussels URUGUAY Pereira Rossell Hospital, Montevideo CROATIA Sveti Duh Hospital, Zagreb GREECE Alexandra Maternity, Athens 1 3 4

Noticias News Nouvelles

Recruitment Tips Noticias News Nouvelles Volume 6 Issue 7 July 31, 2007 University of Toronto Maternal, Infant and Reproductive Health Research Unit at the Women s College Research Institute 7 th Floor,