Noticias News Nouvelles

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Noticias News Nouvelles The Centre for Mother, Infant, and Child Research 7 th Floor, 790 Bay Street Toronto ON CANADA M5G 1N8 Tel: 1 416 351 2533 Fax: 1 416 351 3771 email: tbs@sw.ca website: www.

1 Noticias News Nouvelles The Centre for Mother, Infant, and Child Research 7 th Floor, 790 Bay Street Toronto ON CANADA M5G 1N8 Tel: Fax: tbs@sw.ca website: V O L U M E 9, I S S U E 2 F E B R U A R Y 2 8, Overall Total: 2266 Total this month: 44! I N S I D E T H I S I S S U E European & Middle Eastern Colaborators Meeting Argentina Meeting North American Colaborators Meeting Australian Meeting Upcoming Meetings... European and Middle Eastern Meeting The European & Middle Eastern Colaborators Meeting is a few days away and final plans are being made for those participating in this meeting. An important with final information regarding the agenda and dinner venue has been sent. If you did not receive this information, please contact the Data Coordinating Centre as soon as possible. Housekeeping 3 Recruitment Excellence Recruitment Table 2yr Table Argentina Meeting Dr Mario Palermo of Posadas Hospital in Buenos Aires, Argentina, will be hosting a local TBS meeting on Thursday April 22nd, Dr Jon Barrett will be present at the meeting to discuss the study and answer any questions. If you are in Argentina and would like more information about this meeting, please contact Dr Palermo or the TBS Data Coordinating Centre.

2 P A G E 2 TBS Meetings (continued)... North American Meeting In case you missed the announcement in the last Newsletter, we will be hosting a Colaborators Meeting for our North American centres on October 17 18, 2010 in Banff, Canada. The meeting will be held at the Rimrock Hotel. We hope you have marked your calendars as we would like to see all our Canadian and American centres there! Australian Meeting We are in the early stages of planning a Colaborators meeting for our Australian centres. The meeting will take place on July 1st, 2010 in Sydney, Australia. Stay tuned for more information. Please mark your calendars and plan to join us!

3 P A G E 3 Housekeeping Please note the importance of obtaining an ultrasound within 7 days of randomization and record a valid date on Entry form, question 6. As a reminder, section of the protocol states: An ultrasound should be performed within 7 days prior to randomisation to confirm that both fetuses are alive, determine the estimated fetal weights, the presentation of both fetuses, to rule out contraindications to labour or vaginal delivery and to confirm that twins are diamniotic if not previously determined. Recruitment Excellence Congratulations to Dr Maria Mohedano de Duhalde and the team at Hospital Avellaneda, Tucuman, Argentina; Dr Renato Augusto Moreira de Sa and the team at Maternidade Escola da UFRJ, Rio de Janeiro, Brazil; Dr Danielly Scaranello Nunes Santana and the team at Hospital Universitario de Jundiai, Jundiai, Brazil; Dr Luis Leighton and the team at Hospital Dr Gustavo Fricke, Vina del Mar, Chile; Dr Tamas Major and the team at University of Debrecen, Debrecen, Hungary; Dr Marwan Hakim and the team at Nazareth Hospital (EMMS), Nazareth, Israel; Dr Dalia Mansour-Schwake and the team at Holy Family Hospital, Nazareth, Israel; and Dr Jim Thornton and the team at Nottingham City Hospital, Nottingham, UK; Keep up the excellent work! We will be sending a gold seal to place on your Certificate of Achievement.

4 P A G E 4 Twin Birth Study Recruitment (Projected sample size of 2800) February 28, 2010 Annual Jun Jul - Nov Jan Feb Grand Goal Total COUNTRY ARGENTINA BRAZIL CANADA ISRAEL POLAND UK CHILE EGYPT AUSTRALIA SERBIA USA THE NETHERLANDS JAMAICA ESTONIA SPAIN JORDAN HUNGARY ROMANIA GERMANY BELGIUM CROATIA GREECE Total CENTRES BY COUNTRY (Shaded area is prior to start-up) ARGENTINA Hospital LC Lagomaggiore, Mendoza Hospital Posadas, Buenos Aires Hospital Ramon Carrillo, Santiago del Estero Hospital Avellaneda, Tucuman Hospital JR Vidal, Corrientes Hospital Penna, Bahia Blanca Hospital Sarda, Buenos Aires Hospital Angela Iglesia de Llano, Corrientes Hospital Juan A Fernandez, Buenos Aires Hospital Alvarez, Buenos Aires Centre(s) that are no longer recruiting 0 10 BRAZIL University of Campinas, Campinas Maternidade Escola da UFRJ, Rio de Janeiro University of Pernambuco, Recife Hospital Universitario de Jundiai, Jundiai Maternidade Escola de Vila Nova Cachoeirinha, Sao Paulo Hospital Universitario Antonio Pedro, Niteroi Hospital Sao Lucas, Porto Alegre Perinatal, Rio de Janeiro ISCMPA-Maternidade Mario Totta, Porto Alegre Botucatu Medical School, Botucatu Hospital das Clinicas da UFPE, Recife Hospital Materno Infantil, Goiania Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife 8 1 1

5 PAGE 5 Annual Jun Jul - Nov Jan Feb Grand Goal Total CANADA Sunnybrook Health Sciences Centre, Toronto IWK Health Centre, Halifax Regina General Hospital, Regina Trillium Health Centre, Mississauga Lions Gate Hospital, Vancouver Foothills Medical Centre, Calgary St Joseph's Health Care, London SMBD Jewish General Hospital, Montreal Royal University Hospital, Saskatoon Royal Columbian Hospital, New Westminster North Bay General Hospital, North Bay Women s Health Centre, St John's Toronto East General, Toronto Children's & Women's Health Centre of BC, Vancouver Centre(s) that are no longer recruiting 0 36 ISRAEL Nazareth Hospital (EMMS), Nazareth Ma'ayney HaYeshua Medical Center, Bnei Brak Edith Wolfson Medical Center, Holon Holy Family Hospital, Nazareth HaEmek Medical Center, Afula Poriya Government Hospital, Tiberias Bnai Zion Medical Center, Haifa Hillel Yaffe Medical Center, Hadera POLAND University School of Medical Sciences, Poznan Polish Mothers Memorial Hospital, Lodz Medical University of Gdansk, Gdansk UK Bradford Royal Infirmary, Bradford Nottingham City Hospital, Nottingham Basildon & Thurrock University, Basildon Derriford Hospital, Plymouth Liverpool Women's Hospital, Liverpool Queens Medical Centre, Nottingham Queen Elizabeth Hospital, King's Lynn University Hospital of North Staffordshire, Stoke-on-Trent Lewisham Hospital, London CHILE Hospital Dr Gustavo Fricke, Vina del Mar Hospital Dr Sotero del Rio, Puente Alto EGYPT Assiut University Hospital, Assiut AUSTRALIA Ipswich Hospital, Ipswich Mater Mothers' Hospital, Brisbane St George Hospital, Sydney Toowoomba Base Hospital, Toowoomba Monash Medical Centre, Clayton Logan Hospital, Meadowbrook Townsville Hospital, Townsville Women's and Children's Hospital, Adelaide SERBIA University of Belgrade, Belgrade USA East Bay Perinatal Medical Associates, Oakland University of Miami, Miami Maricopa Medical Center, Phoenix University of South Carolina, Columbia University of Iowa Hospitals and Clinics, Iowa City Centre(s) that are no longer recruiting 0 4

6 PAGE 6 Annual Jun Jul - Nov Jan Feb Grand Goal Total THE NETHERLANDS Atrium Medical Center, Heerlen Academisch Ziekenhuis Maastricht, Maastricht Sint Lucas Andreas Ziekenhuis, Amsterdam Maxima Medical Centre, Veldhoven Centre(s) that are no longer recruiting 0 7 JAMAICA University Hospital of the West Indies, Kingston ESTONIA Tartu University Hospital - Women's Clinic, Tartu SPAIN Hospital Clinic-University of Barcelona, Barcelona JORDAN Islamic Hospital, Amman HUNGARY University of Debrecen, Debrecen ROMANIA University of Pharmacy and Medicine, Cluj-Napoca GERMANY Ludwig Maximilians University of Munich, Munich CUB - Virchow Klinikum, Berlin CUB - Benjamin Franklin, Berlin BELGIUM Centre(s) that are no longer recruiting 0 15 CROATIA Centre(s) that are no longer recruiting 0 9 GREECE Centre(s) that are no longer recruiting 0 4 Centres awaiting first patient: [COUNTRY: Hospital, City (annual goal)] [month/year start-up package sent] ARGENTINA: Hospital JM Cullen, Santa Fe (4) [01/10]; AUSTRALIA: Royal North Shore, St Leonards (3) [11/06]; CANADA:St Paul s Hospital, Vancouver (3) [01/09]; QATAR: Hamad Medical Corporation, Doha (23) [11/09]; UK: Aberdeen Maternity, Aberdeen (6) [11/06]; USA: Washington University, St Louis (5) [01/07];

7 PAGE 7 TBS 2 Year Follow-up The status of the TBS 2 Year Follow-up is displayed in the following table for centres that recruited patients. Centres are listed according to the total number of recruits by country and centre. See below for the number of follow-up assessments performed by your centre! Let's aim for 100% follow-up!! Status Totals As of February 2010 COUNTRY ARGENTINA BRAZIL CANADA ISRAEL POLAND UK CHILE EGYPT AUSTRALIA SERBIA USA THE NETHERLANDS JAMAICA ESTONIA SPAIN JORDAN HUNGARY ROMANIA BELGIUM GERMANY CROATIA GREECE Total % 89.6% 83.8% 80.7% 72.2% 3.1% 46% CENTRES BY COUNTRY (Shaded area is prior to start-up) ARGENTINA Hospital LC Lagomaggiore, Mendoza Hospital Posadas, Buenos Aires Hospital Ramon Carrillo, Santiago del Estero Hospital Avellaneda, Tucuman Hospital JR Vidal, Corrientes Hospital Penna, Bahia Blanca Hospital Sarda, Buenos Aires Hospital Angela Iglesia de Llano, Corrientes Hospital Juan A Fernandez, Buenos Aires Hospital Ramos Mejia, Buenos Aires Hospital Alvarez, Buenos Aires BRAZIL University of Campinas, Campinas Maternidade Escola da UFRJ, Rio de Janeiro University of Pernambuco, Recife Hospital Universitario de Jundiai, Jundiai Maternidade Escola de Vila Nova Cachoeirinha, Sao Paulo Hospital Universitario Antonio Pedro, Niteroi Hospital Sao Lucas, Porto Alegre Perinatal, Rio de Janeiro ISCMPA-Maternidade Mario Totta, Porto Alegre Botucatu Medical School, Botucatu Hospital das Clinicas da UFPE, Recife Hospital Materno Infantil, Goiania Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife 1 1 CANADA Sunnybrook Health Sciences Centre, Toronto IWK Health Centre, Halifax McMaster University Medical Centre, Hamilton Regina General Hospital, Regina Trillium Health Centre, Mississauga Lions Gate Hospital, Vancouver Mount Sinai Hospital, Toronto Foothills Medical Centre, Calgary St Joseph's Health Care, London SMBD Jewish General Hospital, Montreal Royal Columbian Hospital, New Westminster Royal University Hospital, Saskatoon North Bay General Hospital, North Bay 5 5 Women s Health Centre, St John's Toronto East General, Toronto York Central Hospital, Richmond Hill 1 1 Children's & Women's Health Centre of BC, Vancouver 1 1 ISRAEL Nazareth Hospital (EMMS), Nazareth Ma'ayney HaYeshua Medical Center, Bnei Brak Edith Wolfson Medical Center, Holon Holy Family Hospital, Nazareth HaEmek Medical Center, Afula Poriya Government Hospital, Tiberias Bnai Zion Medical Center, Haifa Hillel Yaffe Medical Center, Hadera POLAND Univ School of Medicine, Poznan Polish Mothers Memorial Hospital, Lodz Medical University of Gdansk, Gdansk UK Bradford Royal Infirmary, Bradford Nottingham City Hospital, Nottingham Basildon & Thurrock University, Basildon Derriford Hospital, Plymouth Liverpool Women's Hospital, Liverpool 6 6

8 PAGE 8 Status Totals As of February 2010 Queens Medical Centre, Nottingham 6 6 Queen Elizabeth Hospital, King's Lynn University Hospital of North Staffordshire, Stoke-on-Trent Lewisham Hospital, London 3 3 CHILE Hospital Dr Gustavo Fricke, Vina del Mar Hospital Dr Sotero del Rio, Puente Alto EGYPT Assiut University Hospital, Assiut AUSTRALIA Ipswich Hospital, Ipswich Mater Mothers' Hospital, Brisbane St George Hospital, Sydney Toowoomba Base Hospital, Toowoomba Monash Medical Centre, Clayton Logan Hospital, Meadowbrook Townsville Hospital, Townsville Women's and Children's Hospital, Adelaide 1 1 SERBIA University of Belgrade, Belgrade USA East Bay Perinatal Medical Associates, Oakland University of Miami, Miami Maricopa Medical Center, Phoenix University of South Carolina, Columbia Texas Tech UHSC, Lubbock 2 2 Jamaica Hospital Medical Center, Jamaica University of Iowa Hospitals and Clinics, Iowa City THE NETHERLANDS Atrium Medical Center, Heerlen Academisch Ziekenhuis Maastricht, Maastricht Maaslandziekenhuis Sittard, Sittard Sint Lucas Andreas Ziekenhuis, Amsterdam Maxima Medical Centre, Veldhoven 2 2 JAMAICA University Hospital of the West Indies, Kingston ESTONIA Tartu University Hospital - Women's Clinic, Tartu SPAIN Hospital Clinic-University of Barcelona, Barcelona JORDAN Islamic Hospital, Amman HUNGARY University of Debrecen, Debrecen ROMANIA University of Pharmacy and Medicine, Cluj-Napoca BELGIUM Vrije Universiteit Brussel, Brussels GERMANY Ludwig Maximilians University of Munich, Munich CUB - Virchow Klinikum, Berlin 3 3 CUB - Benjamin Franklin, Berlin CROATIA Sveti Duh Hospital, Zagreb GREECE Alexandra Maternity, Athens 1 3 4

Noticias News Nouvelles

Noticias News Nouvelles Volume 6 Issue 8 August 31, 2007 University of Toronto Maternal, Infant and Reproductive Health Research Unit at the Women s College Research Institute 7 th Floor, 790 Bay Street