Foundation; Initiative for Medicines, Access & Eli Lilly & Co.; Avid. Vosevi 7,429, Oct-17

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1 Trial Drug (if applicable) Patent No. Filed Date Petitioner(s) Patent Owner(s) Inst. Dec. Outcome Details of FWD <Information obtained primarily from Lex Machina and public sources on the Internet. If any errors are identified, please contact Lisa Mandrusiak at Oblon.> IPR Humira 9,512,216 2-Oct-17 Sandoz, Inc. AbbVie Biotechnology Ltd. N/A Pending N/A IPR Herceptin 7,846,441 3-Oct-17 Pfizer, Inc. Genentech, Inc. Denied Pending N/A Hologic, Inc.; Gen-Probe IPR ,221,581 4-Oct-17 Incorporated Enzo Life Sciences Inc. N/A Pending N/A Sawai USA, Inc.; Sawai IPR Myrbetriq 6,346, Oct-17 Pharmaceutical Co., Ltd. Astellas Pharma US, Inc. N/A Pending N/A APS GP LLC; Argentum Pharmaceuticals LLC; APS GP IPR Uceris 9,320, Oct-17 Investors LLC; et al. Cosmo Technologies Ltd. N/A Pending N/A IPR Rituxan 8,545,843 2-Nov-17 Pfizer, Inc. Biogen, Inc. N/A Pending N/A IPR Vosevi 7,429, Oct-17 IPR ,623, Oct-17 Thermo Fisher Scientific, Inc. Bio-Rad Laboratories, Inc. N/A Settled pre-institution N/A IPR ,623, Oct-17 Thermo Fisher Scientific, Inc. Bio-Rad Laboratories, Inc. N/A Pending N/A IPR ,592, Nov-17 IPR IPR IPR IPR IPR Vosevi 7,964, Oct-17 Vosevi 7,964, Oct-17 Vosevi 8,334, Oct-17 Vosevi 8,334, Oct-17 Vosevi 8,735,372 9-Nov-17 Eli Lilly & Co.; Avid Radiopharmaceuticals, Inc. Piramal Imaging SA N/A Pending N/A

2 IPR IPR Vosevi 8,633, Oct-17 Vosevi 9,284,342 2-Nov-17 IPR Abraxane 8,138,229 9-Nov-17 Ltd.; Apotex Inc.; et al. Abraxis Bioscience LC N/A Pending N/A IPR Abraxane 7,820,788 9-Nov-17 Ltd.; Apotex Inc.; et al. Abraxis Bioscience LC N/A Pending N/A IPR Abraxane 7,923,536 9-Nov-17 Ltd.; Apotex Inc.; et al. Abraxis Bioscience LC N/A Pending N/A IPR Humira 9,187,559 6-Nov-17 Sandoz, Inc. AbbVie Biotechnology Ltd. N/A Pending N/A IPR Abraxane 7,820,788 9-Nov-17 IPR Abraxane 7,923,536 9-Nov-17 IPR Abraxane 8,138,229 9-Nov-17 IPR Kerydin 9,549, Nov-17 IPR Kerydin 9,566, Nov-17 IPR Kerydin 9,566, Nov-17 IPR Kerydin 9,572, Nov-17

3 IPR Minivelle 9,724,310 4-Dec-17 IPR Minivelle 9,730,900 4-Dec-17 IPR ,382, Dec-17 Mylan Pharmaceuticals, Inc.; Mylan Technologies, Inc. Noven Pharmaceuticals, Inc. N/A Pending N/A Mylan Pharmaceuticals, Inc.; Mylan Technologies, Inc. Noven Pharmaceuticals, Inc. N/A Pending N/A Provepharm Life Solutions; Provepharm SAS; Provepharm Inc. Wista Laboratories Ltd. N/A Pending N/A IPR Rituxan 9,296,821 1-Dec-17 Pfizer, Inc. Biogen, Inc. N/A Pending N/A Sanofi S.A.; SK Chemicals Co., IPR ,492, Ltd.; Sanofi Pasteur, Inc. Pfizer, Inc. N/A Pending N/A Sanofi S.A.; SK Chemicals Co., IPR ,492, Ltd.; Sanofi Pasteur, Inc. Pfizer, Inc. N/A Pending N/A IPR ,846, Nov-17 Samsung Bioepis Co., Ltd. Genentech, Inc. N/A Pending N/A IPR ,393,256 6-Dec-17 IPR Rituxan 9,504,744 1-Dec-17 Pfizer, Inc. Biogen, Inc. N/A Pending N/A Trans Ova Genetics, LC; IPR ,372,422 4-Dec-17 Intrexon Corporation XY, LLC N/A Pending N/A Trans Ova Genetics, LC; IPR ,652,769 1-Dec-17 Intrexon Corporation XY, LLC N/A Pending N/A Mylan Pharmaceuticals, Inc.; Horizon Pharma, Inc.; Pozen IPR Vimovo 9,393,208 4-Dec-17 Mylan Technologies, Inc. Inc. N/A Pending N/A IPR Rituxan 8,329, Dec-17 Pfizer, Inc. Biogen, Inc. N/A Pending N/A IPR Mydayis 8,846, Dec-17 KVK-Tech, Inc.; Abhai, LLC Shire PLC N/A Pending N/A IPR ,718,852 8-Dec-17 Illumina, Inc. IPR Mydayis 9,173, Dec-17 KVK-Tech, Inc.; Abhai, LLC Shire PLC N/A Pending N/A IPR ,320, Dec-17 IPR ,719, Dec-17 Illumina, Inc. Bioriginal Food & Science Corp.; Rimfrost New Zealand Ltd.; Emerald Fisheries AS; Rimfrost USA, LLC; et al. Aker BioMarine Antarctic AS N/A Pending N/A

4 IPR ,708, Dec-17 Illumina, Inc. Provepharm Life Solutions; Provepharm SAS; Provepharm IPR ,675, Dec-17 Inc. Wista Laboratories Ltd. N/A Pending N/A IPR Herceptin 6,339, Dec-17 Pfizer, Inc. Genentech, Inc. N/A Pending N/A IPR Herceptin 9,249, Dec-17 Pfizer, Inc. Genentech, Inc. N/A Pending N/A IPR Avastin 9,795,672 5-Jan-18 Pfizer, Inc. Genentech, Inc. N/A Pending N/A IPR ,725, Dec-17 Illumina, Inc. Vosevi 8,889, Dec-17 IPR IPR ,636, Dec-17 Sharp & Dohme Corp. Microspherix LLC N/A Pending N/A IPR ,636, Dec-17 Sharp & Dohme Corp. Microspherix LLC N/A Pending N/A IPR ,562, Dec-17 EnviroLogix Inc. Ionian Technologies, Inc. N/A Pending N/A IPR ,562, Dec-17 EnviroLogix Inc. Ionian Technologies, Inc. N/A Pending N/A APS GP LLC; Argentum Pharmaceuticals LLC; APS GP IPR Viibryd 8,673,921 5-Jan-18 Investors LLC; et al. Merck Patentgesellschaft N/A Pending N/A Stichting Sanquin IPR ,352,037 8-Jan-18 Forty Seven, Inc. Bloedvoorziening N/A Pending N/A Lupin Pharmaceuticals, Inc.; IPR Ravicti 9,561, Jan-18 Lupin Ltd. Horizon Therapeutics, LLC N/A Pending N/A Hikma Pharmaceuticals PLC; West-Ward Pharmaceuticals Novartis Pharmaceuticals IPR Afinitor 8,410, Jan-18 International Ltd. Corp. N/A Pending N/A Andrx Corp.; Andrx Labs, LLC; Fortamet ; Andrix Laboratories, Inc.; Actoplus Met Andrx Laboratories (NJ), Inc.; IPR XR 6,790, Jan-18 Aurobindo Pharma USA, Inc. Andrx EU Ltd.; et al. N/A Pending N/A IPR ,074,262 6-Feb-18

5 IPR ,074,262 6-Feb-18 IPR ,697,352 6-Feb-18 IPR ,697,352 6-Feb-18 IPR ,821,835 9-Feb-18 Sharp & Dohme Corp. Microspherix LLC N/A Pending N/A IPR Dapsone 9,161, Feb-18 IPR OxyContin 9,492, Feb-18 Kashiv Pharma, LLC Amneal Pharmaceuticals LLC; Amneal Pharmaceuticals of New York LLC Allergan, Inc. N/A Pending N/A Purdue Pharma L.P.; The P.F. Laboratories, Inc. N/A Pending N/A IPR ,404, Feb-18 Moderna Therapeutics, Inc. Protiva Biotherapeutics, Inc. N/A Pending N/A IPR Revlimid 8,741, Feb-18 Apotex Inc. Celgene Corporation N/A Pending N/A IPR OxyContin 9,492, Feb-18 Kashiv Pharma, LLC Purdue Pharma L.P.; The P.F. Laboratories, Inc. N/A Pending N/A IPR ,364,435 5-Mar-18 Moderna Therapeutics, Inc. Protiva Biotherapeutics, Inc. N/A Pending N/A IPR ,423, Mar-18 L'Oréal USA, Inc.; L'Oréal S.A. IPR ,645, Mar-18 L'Oréal USA, Inc.; L'Oréal S.A. IPR ,546, Mar-18 IPR ,370, Mar-18 Indivior, Inc. IPR ,868, Mar-18 Illumina, Inc. IPR Eliquis 9,326,945 5-Apr-18 Oxford Nanopore Technologies, Inc.; Metrichor, Ltd., Oxford Nanopore Techs. Ltd. Mylan, Inc.; Mylan N.V.; Mylan Pharmaceuticals, Inc. University of Massachusetts Medical School; Carmel Labs, LLC. N/A Pending N/A University of Massachusetts Medical School; Carmel Labs, LLC. N/A Pending N/A Pacific Biosciences of California, Inc. N/A Pending N/A Rhodes Pharmaceuticals L.P. N/A Pending N/A Pfizer, Inc.; Bristol-Myers Squibb Company N/A Pending N/A

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