The Burden of HPV Related Cancers in Kentucky

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1 The Burden of HPV Related Cancers in Kentucky Presented on November 15, 2017 by Katie Bathje, Kentucky Cancer Consortium Many thanks to: Thomas C. Tucker, PhD, MPH Jaclyn Nee, DrPH 1

2 % coverage Adolescent Vaccination Coverage U.S., st dose females: US: 65.1 KY: st dose males: US: 56; KY: 41.6 Complete series females: US: 4.5; KY:.7 Complete series males: US: 7.5; KY: 28.5 MMWR Morb Mortal WklyRep 2017;66: Estimated HPV vaccination coverage with selected doses among adolescents aged 1 17 years, US and KY, National Immunization Survey Teen, United States, US KY st dose females 1st dose males Complete series females MMWR Morb Mortal WklyRep 2017;66: Complete series males 2

3 Impact of Human Papilloma Virus According to the CDC, in general, HPV is thought to be responsible for about 1% of cervical cancers, 75% of vaginal cancers, 6% of vulvar cancers, 6% of penile cancers, 1% of anal cancers, and 70% of oropharyngeal cancers.

4 Age-adjusted rates (per 100,000) KY MS WV DC AR TN LA FL OK MO SC DE NC AL GA ME IN PA OH IL OR NY IA MI MA KS RI WA CT TX NJ NH VA VT ID MT MD CA SD WY AK WI MN NE NM CO ND AZ HI UT HPV Related Cancers, Age-Adjusted Incidence Rate, by State, Kentucky Retrieved from: /index.htm; Accessed November 14, Rate of HPV-Associated Cancers, US & Kentucky, US Kentucky MMWR 2016;65(26):

5 Age adjusted Incidence rate (per 100,000) 16 Cancer Incidence Rates in Kentucky Oral Cavity and Pharynx,

6 Cervical Cancer Incidence Cervical Cancer Incidence Rates Ranked by State ( ) 8th Source: CDC/USCS Website Accessed November 1,

7 Age-Adjusted Rate (per 100,000) Cervix Uteri Invasive Cancer Incidence Rate R² =

8 Age-Adjusted Rate (per 100,000) Age-Adjusted Rate (per 100,000) White vs. Black Cervix Uteri Invasive Cancer Incidence Rate White Black R² = Linear (White) Linear (Black) 8 6 R² = Urban vs. Rural Cervix Uteri Invasive Cancer Incidence Rate R² = 0.28 Urban Cervix Uteri Rural Cervix Uteri Linear (Urban Cervix Uteri) Linear (Rural Cervix Uteri) 8 7 R² =

9 Age-Adjusted Rate (per 100,000) Appalachia vs. Non-Appalachia Cervix Uteri Invasive Cancer Incidence Rate R² = R² = Appalachia Cervix Uteri Non-Appalachia Cervix Uteri Linear (Appalachia Cervix Uteri) Linear (Non- Appalachia Cervix Uteri) Cervical Cancer Mortality

10 Cervical Cancer Mortality Rates Ranked by State ( ) 10th Source: CDC/USCS Website Accessed November 1,

11 Age-Adjusted Rate (per 100,000) Age-Adjusted Rate (per 100,000) 4.5 Overall Cervix Uteri Cancer Mortality Rates R² = White vs. Black Cervix Uteri Cancer Mortality Rates R² = White Black Linear (White) Linear (Black) 2 R² =

12 Age-Adjusted Rate (per 100,000) Age-Adjusted Rate (per 100,000) Urban vs. Rural Cervix Uteri Cancer Mortality Rates R² = R² = Urban Rural Linear (Urban) Linear (Rural) Appalachia vs. Non-Appalachia Cervix Uteri Cancer Appalachia Mortality Rates Non-Appalachia 4 R² = Linear (Appalachia) Linear (Non- Appalachia) 2 R² =

13 Area Development District Cervical Cancer by Area Development District in KY, High School Education, Pap Rate (%) 2012 Age-Adjusted Incidence Percent Rank Percent Rank Rate Rank Overall Rank Kentucky River Cumberland Valley Barren River Big Sandy Lake Cumberland Fivco Buffalo Trace Pennyrile Gateway Purchase Kipda Northern Kentucky Bluegrass Lincoln Trail Green River

14 % coverage Estimated HPV vaccination coverage with selected doses among adolescents aged 1 17 years, US and KY, National Immunization Survey Teen, United States, US KY st dose females 1st dose males Complete series females MMWR Morb Mortal WklyRep 2017;66: Complete series males The Hope of HPV Vaccine Uptake is rising Since its introduction 11 years ago, the vaccine: covers more strains of HPV use has been extended to males as well as females the dosage has dropped from three to two shots the cost is fully covered by private insurance and public programs The vaccine holds the promise to safely and dramatically reduce rate of and prevent many kinds of cancers that have long been responsible for the deaths of women and men across the United States and the world. 14

15 Thank you! Katie Bathje, Kentucky Cancer Consortium 15

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